Loading…
Management of osteonecrosis of the femoral head in children with sickle cell disease: Results of conservative and operative treatments at skeletal maturity
Purpose Sickle cell disease (SCD) is the most common cause of femoral head osteonecrosis (ONFH) during childhood with an overall prevalence of 10%. In children, spontaneous revascularization can occur, as in Legg-Calve-Perthes disease. Consequently, the aim of treatment is to restore proper hip cont...
Saved in:
| Published in: | Journal of children's orthopaedics 2018-02, Vol.12 (1), p.47-54 |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that this one cites Items that cite this one |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | cdi_FETCH-LOGICAL-c474t-1b7d3b651de27f9469fe8dbd073e272afe4f88b77bb74f9407d5338a47a1f6b13 |
|---|---|
| cites | cdi_FETCH-LOGICAL-c474t-1b7d3b651de27f9469fe8dbd073e272afe4f88b77bb74f9407d5338a47a1f6b13 |
| container_end_page | 54 |
| container_issue | 1 |
| container_start_page | 47 |
| container_title | Journal of children's orthopaedics |
| container_volume | 12 |
| creator | Mallet, C. Abitan, A. Vidal, C. Holvoet, L. Mazda, K. Simon, A.-L. Ilharreborde, B. |
| description | Purpose
Sickle cell disease (SCD) is the most common cause of femoral head osteonecrosis (ONFH) during childhood with an overall prevalence of 10%. In children, spontaneous revascularization can occur, as in Legg-Calve-Perthes disease. Consequently, the aim of treatment is to restore proper hip containment to prevent joint arthritis. This is the first study reporting long-term results at skeletal maturity of non-operative and surgical treatments for ONFH in SCD children.
Methods
All children with ONFH due to SCD were retrospectively reviewed. At initial evaluation, extension of osteonecrosis was radiographically defined using Catterall, lateral pillar Herring and Ficat classifications. Subluxation of the femoral head with Reimers migration index > 30% required surgical treatment including femoral varus osteotomy and/or pelvic osteotomies. Conservative treatment including non-weight bearing and physiotherapy was performed in the remaining cases. Outcomes were assessed at skeletal maturity using the Harris Hip Score (HHS) and the Stulberg classification. Total hip arthroplasty and Stulberg 5 were defined as failures.
Results
A total of 25 hips in 17 patients were included (mean follow-up 7.5 years SD 3.4). Mean age at diagnosis was 11.4 years SD 2.9. In all, 15 hips (60%) were classified Catterall 3 and 4 and Herring B and C. A total of 13 patients (52%) underwent surgical treatment. At skeletal maturity, mean HHS was good (81 SD 17), 12 hips (48%) were classified Stulberg 1 and 2, seven hips (28%) were classified Stulberg 3 and 4.
Conclusion
Both treatments led to good functional results with 75% of congruent hips at skeletal maturity.
Level of Evidence
IV |
| doi_str_mv | 10.1302/1863-2548.12.170141 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5813125</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sage_id>10.1302_1863-2548.12.170141</sage_id><sourcerecordid>2004397828</sourcerecordid><originalsourceid>FETCH-LOGICAL-c474t-1b7d3b651de27f9469fe8dbd073e272afe4f88b77bb74f9407d5338a47a1f6b13</originalsourceid><addsrcrecordid>eNp9kU1v1DAQhi1ERUvhFyAhS1y47OKvxA4HpKpqAakVEoKz5cSTxm1iL7azqL-lf7ZOtywfB072zLx-Z8YPQq8oWVNO2Duqar5ilVBrytZUEiroE3S0zz7d3xk9RM9TuiakJk2jnqFD1oiqlpU4QneXxpsrmMBnHHocUobgoYshubQk8gC4hylEM-IBjMXO425wo43g8U-XB5xcdzMC7mAcsXUJTIL3-CukecwPDl3wCeLWZLcFbLzFYQNxF-UIJi-tEzYZpxsYIZc-k8lzdPn2BTrozZjg5eN5jL6fn307_bS6-PLx8-nJxaoTUuQVbaXlbV1RC0z2jaibHpRtLZG8JJjpQfRKtVK2rRSlTqStOFdGSEP7uqX8GH3Y-W7mdgLblYHKunoT3WTirQ7G6b8r3g36Kmx1pSinrCoGbx8NYvgxQ8p6cmn5EOMhzEkzQgRvpGKqSN_8I70Oc_RlPc0qJQRrOF0m4jvVAiJF6PfDUKIX-HpBqxfMmpbgAX559frPPfZvftEuArITpIL8d-P_ed4DCfS8sA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2584429311</pqid></control><display><type>article</type><title>Management of osteonecrosis of the femoral head in children with sickle cell disease: Results of conservative and operative treatments at skeletal maturity</title><source>Publicly Available Content Database</source><source>Sage Journals GOLD Open Access 2024</source><source>PubMed Central</source><creator>Mallet, C. ; Abitan, A. ; Vidal, C. ; Holvoet, L. ; Mazda, K. ; Simon, A.-L. ; Ilharreborde, B.</creator><creatorcontrib>Mallet, C. ; Abitan, A. ; Vidal, C. ; Holvoet, L. ; Mazda, K. ; Simon, A.-L. ; Ilharreborde, B.</creatorcontrib><description>Purpose
Sickle cell disease (SCD) is the most common cause of femoral head osteonecrosis (ONFH) during childhood with an overall prevalence of 10%. In children, spontaneous revascularization can occur, as in Legg-Calve-Perthes disease. Consequently, the aim of treatment is to restore proper hip containment to prevent joint arthritis. This is the first study reporting long-term results at skeletal maturity of non-operative and surgical treatments for ONFH in SCD children.
Methods
All children with ONFH due to SCD were retrospectively reviewed. At initial evaluation, extension of osteonecrosis was radiographically defined using Catterall, lateral pillar Herring and Ficat classifications. Subluxation of the femoral head with Reimers migration index > 30% required surgical treatment including femoral varus osteotomy and/or pelvic osteotomies. Conservative treatment including non-weight bearing and physiotherapy was performed in the remaining cases. Outcomes were assessed at skeletal maturity using the Harris Hip Score (HHS) and the Stulberg classification. Total hip arthroplasty and Stulberg 5 were defined as failures.
Results
A total of 25 hips in 17 patients were included (mean follow-up 7.5 years SD 3.4). Mean age at diagnosis was 11.4 years SD 2.9. In all, 15 hips (60%) were classified Catterall 3 and 4 and Herring B and C. A total of 13 patients (52%) underwent surgical treatment. At skeletal maturity, mean HHS was good (81 SD 17), 12 hips (48%) were classified Stulberg 1 and 2, seven hips (28%) were classified Stulberg 3 and 4.
Conclusion
Both treatments led to good functional results with 75% of congruent hips at skeletal maturity.
Level of Evidence
IV</description><identifier>ISSN: 1863-2521</identifier><identifier>EISSN: 1863-2548</identifier><identifier>DOI: 10.1302/1863-2548.12.170141</identifier><identifier>PMID: 29456754</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>Age ; Arthritis ; Cartilage ; Classification ; Hemoglobin ; Joint replacement surgery ; Joint surgery ; Original Clinical ; Orthopedics ; Pain ; Pediatrics ; Physical therapy ; Sickle cell disease ; Traction (Orthopedics)</subject><ispartof>Journal of children's orthopaedics, 2018-02, Vol.12 (1), p.47-54</ispartof><rights>2018 European Pediatric Orthopaedic Society (EPOS), unless otherwise noted. Manuscript content on this site is licensed under Creative Commons Licenses.</rights><rights>2018. This work is published under https://creativecommons.org/licenses/by-nc/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Copyright © 2018, The author(s) 2018 The author(s)</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c474t-1b7d3b651de27f9469fe8dbd073e272afe4f88b77bb74f9407d5338a47a1f6b13</citedby><cites>FETCH-LOGICAL-c474t-1b7d3b651de27f9469fe8dbd073e272afe4f88b77bb74f9407d5338a47a1f6b13</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/2584429311/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2584429311?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,21966,25753,27853,27924,27925,37012,37013,44590,44945,45333,53791,53793,75126</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29456754$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mallet, C.</creatorcontrib><creatorcontrib>Abitan, A.</creatorcontrib><creatorcontrib>Vidal, C.</creatorcontrib><creatorcontrib>Holvoet, L.</creatorcontrib><creatorcontrib>Mazda, K.</creatorcontrib><creatorcontrib>Simon, A.-L.</creatorcontrib><creatorcontrib>Ilharreborde, B.</creatorcontrib><title>Management of osteonecrosis of the femoral head in children with sickle cell disease: Results of conservative and operative treatments at skeletal maturity</title><title>Journal of children's orthopaedics</title><addtitle>J Child Orthop</addtitle><description>Purpose
Sickle cell disease (SCD) is the most common cause of femoral head osteonecrosis (ONFH) during childhood with an overall prevalence of 10%. In children, spontaneous revascularization can occur, as in Legg-Calve-Perthes disease. Consequently, the aim of treatment is to restore proper hip containment to prevent joint arthritis. This is the first study reporting long-term results at skeletal maturity of non-operative and surgical treatments for ONFH in SCD children.
Methods
All children with ONFH due to SCD were retrospectively reviewed. At initial evaluation, extension of osteonecrosis was radiographically defined using Catterall, lateral pillar Herring and Ficat classifications. Subluxation of the femoral head with Reimers migration index > 30% required surgical treatment including femoral varus osteotomy and/or pelvic osteotomies. Conservative treatment including non-weight bearing and physiotherapy was performed in the remaining cases. Outcomes were assessed at skeletal maturity using the Harris Hip Score (HHS) and the Stulberg classification. Total hip arthroplasty and Stulberg 5 were defined as failures.
Results
A total of 25 hips in 17 patients were included (mean follow-up 7.5 years SD 3.4). Mean age at diagnosis was 11.4 years SD 2.9. In all, 15 hips (60%) were classified Catterall 3 and 4 and Herring B and C. A total of 13 patients (52%) underwent surgical treatment. At skeletal maturity, mean HHS was good (81 SD 17), 12 hips (48%) were classified Stulberg 1 and 2, seven hips (28%) were classified Stulberg 3 and 4.
Conclusion
Both treatments led to good functional results with 75% of congruent hips at skeletal maturity.
Level of Evidence
IV</description><subject>Age</subject><subject>Arthritis</subject><subject>Cartilage</subject><subject>Classification</subject><subject>Hemoglobin</subject><subject>Joint replacement surgery</subject><subject>Joint surgery</subject><subject>Original Clinical</subject><subject>Orthopedics</subject><subject>Pain</subject><subject>Pediatrics</subject><subject>Physical therapy</subject><subject>Sickle cell disease</subject><subject>Traction (Orthopedics)</subject><issn>1863-2521</issn><issn>1863-2548</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>AFRWT</sourceid><sourceid>PIMPY</sourceid><recordid>eNp9kU1v1DAQhi1ERUvhFyAhS1y47OKvxA4HpKpqAakVEoKz5cSTxm1iL7azqL-lf7ZOtywfB072zLx-Z8YPQq8oWVNO2Duqar5ilVBrytZUEiroE3S0zz7d3xk9RM9TuiakJk2jnqFD1oiqlpU4QneXxpsrmMBnHHocUobgoYshubQk8gC4hylEM-IBjMXO425wo43g8U-XB5xcdzMC7mAcsXUJTIL3-CukecwPDl3wCeLWZLcFbLzFYQNxF-UIJi-tEzYZpxsYIZc-k8lzdPn2BTrozZjg5eN5jL6fn307_bS6-PLx8-nJxaoTUuQVbaXlbV1RC0z2jaibHpRtLZG8JJjpQfRKtVK2rRSlTqStOFdGSEP7uqX8GH3Y-W7mdgLblYHKunoT3WTirQ7G6b8r3g36Kmx1pSinrCoGbx8NYvgxQ8p6cmn5EOMhzEkzQgRvpGKqSN_8I70Oc_RlPc0qJQRrOF0m4jvVAiJF6PfDUKIX-HpBqxfMmpbgAX559frPPfZvftEuArITpIL8d-P_ed4DCfS8sA</recordid><startdate>201802</startdate><enddate>201802</enddate><creator>Mallet, C.</creator><creator>Abitan, A.</creator><creator>Vidal, C.</creator><creator>Holvoet, L.</creator><creator>Mazda, K.</creator><creator>Simon, A.-L.</creator><creator>Ilharreborde, B.</creator><general>SAGE Publications</general><general>Sage Publications Ltd</general><general>The British Editorial Society of Bone & Joint Surgery</general><scope>AFRWT</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>M0R</scope><scope>M0S</scope><scope>NAPCQ</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>201802</creationdate><title>Management of osteonecrosis of the femoral head in children with sickle cell disease: Results of conservative and operative treatments at skeletal maturity</title><author>Mallet, C. ; Abitan, A. ; Vidal, C. ; Holvoet, L. ; Mazda, K. ; Simon, A.-L. ; Ilharreborde, B.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c474t-1b7d3b651de27f9469fe8dbd073e272afe4f88b77bb74f9407d5338a47a1f6b13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Age</topic><topic>Arthritis</topic><topic>Cartilage</topic><topic>Classification</topic><topic>Hemoglobin</topic><topic>Joint replacement surgery</topic><topic>Joint surgery</topic><topic>Original Clinical</topic><topic>Orthopedics</topic><topic>Pain</topic><topic>Pediatrics</topic><topic>Physical therapy</topic><topic>Sickle cell disease</topic><topic>Traction (Orthopedics)</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mallet, C.</creatorcontrib><creatorcontrib>Abitan, A.</creatorcontrib><creatorcontrib>Vidal, C.</creatorcontrib><creatorcontrib>Holvoet, L.</creatorcontrib><creatorcontrib>Mazda, K.</creatorcontrib><creatorcontrib>Simon, A.-L.</creatorcontrib><creatorcontrib>Ilharreborde, B.</creatorcontrib><collection>Sage Journals GOLD Open Access 2024</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Proquest Nursing & Allied Health Source</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Consumer Health Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Nursing & Allied Health Premium</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of children's orthopaedics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mallet, C.</au><au>Abitan, A.</au><au>Vidal, C.</au><au>Holvoet, L.</au><au>Mazda, K.</au><au>Simon, A.-L.</au><au>Ilharreborde, B.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Management of osteonecrosis of the femoral head in children with sickle cell disease: Results of conservative and operative treatments at skeletal maturity</atitle><jtitle>Journal of children's orthopaedics</jtitle><addtitle>J Child Orthop</addtitle><date>2018-02</date><risdate>2018</risdate><volume>12</volume><issue>1</issue><spage>47</spage><epage>54</epage><pages>47-54</pages><issn>1863-2521</issn><eissn>1863-2548</eissn><abstract>Purpose
Sickle cell disease (SCD) is the most common cause of femoral head osteonecrosis (ONFH) during childhood with an overall prevalence of 10%. In children, spontaneous revascularization can occur, as in Legg-Calve-Perthes disease. Consequently, the aim of treatment is to restore proper hip containment to prevent joint arthritis. This is the first study reporting long-term results at skeletal maturity of non-operative and surgical treatments for ONFH in SCD children.
Methods
All children with ONFH due to SCD were retrospectively reviewed. At initial evaluation, extension of osteonecrosis was radiographically defined using Catterall, lateral pillar Herring and Ficat classifications. Subluxation of the femoral head with Reimers migration index > 30% required surgical treatment including femoral varus osteotomy and/or pelvic osteotomies. Conservative treatment including non-weight bearing and physiotherapy was performed in the remaining cases. Outcomes were assessed at skeletal maturity using the Harris Hip Score (HHS) and the Stulberg classification. Total hip arthroplasty and Stulberg 5 were defined as failures.
Results
A total of 25 hips in 17 patients were included (mean follow-up 7.5 years SD 3.4). Mean age at diagnosis was 11.4 years SD 2.9. In all, 15 hips (60%) were classified Catterall 3 and 4 and Herring B and C. A total of 13 patients (52%) underwent surgical treatment. At skeletal maturity, mean HHS was good (81 SD 17), 12 hips (48%) were classified Stulberg 1 and 2, seven hips (28%) were classified Stulberg 3 and 4.
Conclusion
Both treatments led to good functional results with 75% of congruent hips at skeletal maturity.
Level of Evidence
IV</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>29456754</pmid><doi>10.1302/1863-2548.12.170141</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1863-2521 |
| ispartof | Journal of children's orthopaedics, 2018-02, Vol.12 (1), p.47-54 |
| issn | 1863-2521 1863-2548 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5813125 |
| source | Publicly Available Content Database; Sage Journals GOLD Open Access 2024; PubMed Central |
| subjects | Age Arthritis Cartilage Classification Hemoglobin Joint replacement surgery Joint surgery Original Clinical Orthopedics Pain Pediatrics Physical therapy Sickle cell disease Traction (Orthopedics) |
| title | Management of osteonecrosis of the femoral head in children with sickle cell disease: Results of conservative and operative treatments at skeletal maturity |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-04T20%3A52%3A27IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Management%20of%20osteonecrosis%20of%20the%20femoral%20head%20in%20children%20with%20sickle%20cell%20disease:%20Results%20of%20conservative%20and%20operative%20treatments%20at%20skeletal%20maturity&rft.jtitle=Journal%20of%20children's%20orthopaedics&rft.au=Mallet,%20C.&rft.date=2018-02&rft.volume=12&rft.issue=1&rft.spage=47&rft.epage=54&rft.pages=47-54&rft.issn=1863-2521&rft.eissn=1863-2548&rft_id=info:doi/10.1302/1863-2548.12.170141&rft_dat=%3Cproquest_pubme%3E2004397828%3C/proquest_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c474t-1b7d3b651de27f9469fe8dbd073e272afe4f88b77bb74f9407d5338a47a1f6b13%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2584429311&rft_id=info:pmid/29456754&rft_sage_id=10.1302_1863-2548.12.170141&rfr_iscdi=true |