Contrast-Enhanced Ultrasound Improves the Pathological Outcomes of US-Guided Core Needle Biopsy That Targets the Viable Area of Anterior Mediastinal Masses

Based on the option that ultrasound-guided core needle biopsy (US-CNB) of the enhanced portion of anterior mediastinal masses (AMMs) identified by contrast-enhanced ultrasound (CEUS) would harvest viable tissue and benefit the histological diagnoses, a retrospective study was performed to elucidate...

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Bibliographic Details
Published in:BioMed research international 2018-01, Vol.2018 (2018), p.1-9
Main Authors: Wang, Si-yu, Wang, Yu, Xiang, Jin, Mo, Yun-xian, Ou, Wei, Shan, Hong-bo, Zhou, Jian-hua, Li, Jian
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
B cells
Biomedical research
Biopsy
Biopsy, Large-Core Needle - methods
Blood flow
Cancer therapies
Child
Child, Preschool
Collaboration
Contrast Media - administration & dosage
Correlation analysis
Diagnostic systems
Female
Humans
Image-Guided Biopsy - methods
Laboratories
Lymphoma
Male
Mediastinal Neoplasms - diagnostic imaging
Mediastinal Neoplasms - pathology
Medical imaging
Medical research
Medicine
Middle Aged
Necrosis
Oncology
Ostomy
Patients
Studies
Surgery
Thoracic surgery
Tumors
Ultrasonography - methods
Ultrasound
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Summary:Based on the option that ultrasound-guided core needle biopsy (US-CNB) of the enhanced portion of anterior mediastinal masses (AMMs) identified by contrast-enhanced ultrasound (CEUS) would harvest viable tissue and benefit the histological diagnoses, a retrospective study was performed to elucidate the correlation between the prebiopsy CEUS and diagnostic yield of AMMs and found that CEUS potentially improved the diagnostic yield of AMMs compared with conventional US with a significant increase in the cellularity of samples. Furthermore, the marginal blood flow signals and absence of necrosis can predict the diagnostic yield of AMM. It was concluded that US-CNB of the viable part of AMMs, as verified by CEUS, was able to harvest sufficient tissue with more cellularity that could be used for ancillary studies and improve the diagnostic yield. And CEUS was recommended to those patients with AMMs undergoing repeated US-CNB, with the absence of marginal blood signals or presence of necrosis.
ISSN:2314-6133
2314-6141
DOI:10.1155/2018/9825709