Synthetic polymeric biomaterials for wound healing: a review

Wounds are of a variety of types and each category has its own distinctive healing requirements. This realization has spurred the development of a myriad of wound dressings, each with specific characteristics. It is unrealistic to expect a singular dressing to embrace all characteristics that would...

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Bibliographic Details
Published in:Progress in biomaterials 2018-03, Vol.7 (1), p.1-21
Main Authors: Mir, Mariam, Ali, Murtaza Najabat, Barakullah, Afifa, Gulzar, Ayesha, Arshad, Munam, Fatima, Shizza, Asad, Maliha
Format: Article
Language:English
Subjects:
Alginic acid
Bioengineering
Biomaterials
Biomedical materials
Chemistry and Materials Science
Expenditures
Hydrogels
Materials Science
Medical dressings
Polymer films
Review Paper
Skin
Wound healing
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Summary:Wounds are of a variety of types and each category has its own distinctive healing requirements. This realization has spurred the development of a myriad of wound dressings, each with specific characteristics. It is unrealistic to expect a singular dressing to embrace all characteristics that would fulfill generic needs for wound healing. However, each dressing may approach the ideal requirements by deviating from the ‘one size fits all approach’, if it conforms strictly to the specifications of the wound and the patient. Indeed, a functional wound dressing should achieve healing of the wound with minimal time and cost expenditures. This article offers an insight into several different types of polymeric materials clinically used in wound dressings and the events taking place at cellular level, which aid the process of healing, while the biomaterial dressing interacts with the body tissue. Hence, the significance of using synthetic polymer films, foam dressings, hydrocolloids, alginate dressings, and hydrogels has been reviewed, and the properties of these materials that conform to wound-healing requirements have been explored. A special section on bioactive dressings and bioengineered skin substitutes that play an active part in healing process has been re-examined in this work.
ISSN:2194-0509
2194-0517
DOI:10.1007/s40204-018-0083-4