Disseminated Cutaneous Infection of Mycobacterium colombiense in a Patient with Myelodysplastic Syndrome

Mycobacterium colombiense (M. colombiense) is a member of the Mycobacterium avium complex (MAC). To our knowledge, this is the third case report of an M. colombiense infection. An 80-year-old man, immunocompromised by myelodysplastic syndrome (MDS), developed a skin rash with exfoliation and eruptio...

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Bibliographic Details
Published in:Internal Medicine 2018/02/01, Vol.57(3), pp.423-427
Main Authors: Inagaki, Yuichiro, Ito, Tatsuya, Kato, Tomonori, Ono, Yoshitaka, Sawa, Masashi
Format: Article
Language:English
Subjects:
Antibiotics
broad-range polymerase chain reaction
Case Report
Clarithromycin
Ethambutol
Exanthema
immunocompromised host
Infections
Internal medicine
Lesions
Mycobacterium
Mycobacterium avium complex
Myelodysplastic syndrome
nontuberculous mycobacteria
Polymerase chain reaction
Rifampin
Scalp
Skin
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Summary:Mycobacterium colombiense (M. colombiense) is a member of the Mycobacterium avium complex (MAC). To our knowledge, this is the third case report of an M. colombiense infection. An 80-year-old man, immunocompromised by myelodysplastic syndrome (MDS), developed a skin rash with exfoliation and eruption on his face and scalp. Mycobacteria were detected in pus samples. Broad-range polymerase chain reaction (PCR) revealed the mycobacteria to be M. colombiense. The lesions resolved after daily administration of rifampicin, ethambutol, and clarithromycin. In conclusion, broad-range PCR identified this rare mycobacterium, allowing for the administration of appropriate combination antibiotic therapy.
ISSN:0918-2918
1349-7235
DOI:10.2169/internalmedicine.7890-16