Evaluation of Individual and Combined Markers of Urine Dipstick Parameters and Total Lymphocyte Count as a Substitute for CD4 Count in Low-Resource Communities in Ghana

We evaluated the individual and combined levels of urine dipstick and total lymphocyte count (TLC) as surrogate markers for CD4 count in a low-resource community in Ghana. This cross-sectional study recruited 200 HIV-infected patients from the Saint Francis Xavier Hospital, Assin Fosu, Ghana. Comple...

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Bibliographic Details
Published in:Disease markers 2018-01, Vol.2018 (2018), p.1-7
Main Authors: Osaah, Esther, Jommo, Juliana, Donkor, Sampson, Oppong Afranie, Bright, Amankwaa, Bright, Acheampong, Emmanuel, Obirikorang, Christian, Odame Anto, Enoch, Hope, Isaac
Format: Article
Language:English
Subjects:
Adolescent
Adult
Antiretroviral drugs
Blood
CD4 antigen
CD4 Lymphocyte Count
Cell number
Communities
Cross-Sectional Studies
Disease Progression
Ethylenediaminetetraacetic acid
Female
Ghana
Hematuria
HIV
HIV Infections - immunology
HIV Infections - urine
HIV patients
Human immunodeficiency virus
Humans
Lymphocyte Count
Lymphocytes
Male
Markers
Medical examination
Medical research
Medicine, Experimental
Middle Aged
Patients
Poverty
Proteinuria
Proteinuria - urine
Sensitivity
Sensitivity and Specificity
Substitutes
Urine
Young Adult
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Summary:We evaluated the individual and combined levels of urine dipstick and total lymphocyte count (TLC) as surrogate markers for CD4 count in a low-resource community in Ghana. This cross-sectional study recruited 200 HIV-infected patients from the Saint Francis Xavier Hospital, Assin Fosu, Ghana. Complete blood count, CD4 count, and urine dipstick analysis were measured for participants. The threshold values were determined as
ISSN:0278-0240
1875-8630
DOI:10.1155/2018/7485942