Update on colchicine, 2017

Abstract Colchicine is an ancient medication that is currently approved for the treatment of gout and FMF. However, colchicine has a wide range of anti-inflammatory activities, and studies indicate that it may be beneficial in a variety of other conditions. This paper reviews the evidence for the we...

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Bibliographic Details
Published in:Rheumatology (Oxford, England) England), 2018-01, Vol.57 (suppl_1), p.i4-i11
Main Authors: Slobodnick, Anastasia, Shah, Binita, Krasnokutsky, Svetlana, Pillinger, Michael H.
Format: Article
Language:English
Subjects:
Cardiovascular disease
Cardiovascular Diseases - etiology
Cardiovascular Diseases - prevention & control
Colchicine
Colchicine - therapeutic use
Coronary artery
Coronary artery disease
Gout
Gout - complications
Gout - drug therapy
Gout Suppressants - therapeutic use
Humans
Inflammation
Reviews
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Summary:Abstract Colchicine is an ancient medication that is currently approved for the treatment of gout and FMF. However, colchicine has a wide range of anti-inflammatory activities, and studies indicate that it may be beneficial in a variety of other conditions. This paper reviews the evidence for the well-established use of colchicine in gout, as well as several other rheumatic diseases. In addition, we highlight the potential benefit of colchicine in cardiac disease, including coronary artery disease in patients both with and without gout.
ISSN:1462-0324
1462-0332
DOI:10.1093/rheumatology/kex453