Disagreement between splenic switch-off and myocardial T1-mapping after caffeine intake

Caffeine is an adenosine receptor antagonist and a possible cause of inadequate stress perfusion. Splenic switch-off (SSO) and splenic rest-stress T1-mapping have been proposed as indicators of stress adequacy during perfusion cardiac magnetic resonance (CMR). We compared myocardial rest-stress T1-m...

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Bibliographic Details
Published in:The International Journal of Cardiovascular Imaging 2018-04, Vol.34 (4), p.625-632
Main Authors: Kuijpers, Dirkjan, van Dijk, Randy, van Assen, Marly, Kaandorp, Theodorus A. M., van Dijkman, Paul R. M., Vliegenthart, Rozemarijn, van der Harst, Pim, Oudkerk, Matthijs
Format: Article
Language:English
Subjects:
Adenosine
Adequacy
Caffeine
Cardiac Imaging
Cardiology
Coffee
Health risk assessment
Heart diseases
Imaging
Indicators
Ischemia
Magnetic resonance
Mapping
Medicine
Medicine & Public Health
Myocardial ischemia
Myocardium
Original Paper
Patients
Perfusion
Radiology
Rest
Spleen
Stress
Stresses
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Summary:Caffeine is an adenosine receptor antagonist and a possible cause of inadequate stress perfusion. Splenic switch-off (SSO) and splenic rest-stress T1-mapping have been proposed as indicators of stress adequacy during perfusion cardiac magnetic resonance (CMR). We compared myocardial rest-stress T1-mapping with SSO and splenic rest-stress T1-mapping in patients with and without recent coffee intake. We analyzed 344 consecutive patients suspected of myocardial ischemia with adenosine perfusion CMR. All 146 normal CMR studies with a normal T1-rest of the myocardium, used as standard of reference, were included and divided in two groups. 22 patients accidentally ingested coffee
ISSN:1569-5794
1573-0743
1875-8312
DOI:10.1007/s10554-017-1274-0