Multipath Curved Planar Reformations of Peripheral CT Angiography: Diagnostic Accuracy and Time Efficiency

Objectives To compare diagnostic performance and time efficiency between 3D multipath curved planar reformations (mpCPRs) and axial images of CT angiography for the pre-interventional assessment of peripheral arterial disease (PAD), with digital subtraction angiography as the standard of reference....

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Bibliographic Details
Published in:Cardiovascular and interventional radiology 2018-05, Vol.41 (5), p.718-725
Main Authors: Schreiner, Markus M., Platzgummer, Hannes, Unterhumer, Sylvia, Weber, Michael, Mistelbauer, Gabriel, Groeller, Eduard, Loewe, Christian, Schernthaner, Ruediger E.
Format: Article
Language:English
Subjects:
Accuracy
Adult
Aged
Aged, 80 and over
Angiography
BIOMEDICAL RADIOGRAPHY
BLOOD VESSELS
Cardiology
Cardiovascular system
Clinical Investigation
Computed tomography
Computed Tomography Angiography - methods
DIAGNOSIS
Diagnostic systems
Digital imaging
Female
Females
Humans
IMAGE PROCESSING
Imaging
Imaging, Three-Dimensional - methods
Male
Medical diagnosis
Medical imaging
Medicine
Medicine & Public Health
Middle Aged
Multidetector Computed Tomography
Nuclear Medicine
Peripheral Arterial Disease - diagnostic imaging
Prospective Studies
Radiology
RADIOLOGY AND NUCLEAR MEDICINE
RADIOSENSITIVITY
Readers
Reproducibility of Results
Sensitivity and Specificity
Stenosis
Time
Ultrasound
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Summary:Objectives To compare diagnostic performance and time efficiency between 3D multipath curved planar reformations (mpCPRs) and axial images of CT angiography for the pre-interventional assessment of peripheral arterial disease (PAD), with digital subtraction angiography as the standard of reference. Methods Forty patients (10 females, mean age 72 years), referred to CTA prior to endovascular treatment of PAD, were prospectively included and underwent peripheral CT angiography. A semiautomated toolbox was used to render mpCPRs. Twenty-one arterial segments were defined in each leg; for each segment, the presence of stenosis > 70% was assessed on mpCPRs and axial images by two readers, independently, with digital subtraction angiography as gold standard. Results Both readers reached lower sensitivity (Reader 1: 91 vs. 94%, p  = 0.08; Reader 2: 89 vs. 93%, p  = 0.03) but significantly higher specificity (Reader 1: 94 vs. 89%, p  
ISSN:0174-1551
1432-086X
DOI:10.1007/s00270-017-1846-3