S200. HYPOVITAMINOSIS D IN SCHIZOPHRENIA: PREVALENCE AND ASSOCIATED CLINICAL CHARACTERISTICS

• Published in: Schizophrenia bulletin 2018-04, Vol.44 (suppl_1), p.S403-S403
• Main Authors: Nefzi, Rahma, Larnaout, Amine, Ben Ammar, Hanen, Khelifa, Emira, Aissa, Amina, Hechmi, Zouhaier El
• Format: Article
• Language: English
• Subjects: Abstracts
• ISSN: 0586-7614; 1745-1701
• DOI: 10.1093/schbul/sby018.987

Abstract Background Schizophrenia is an invalid and severe neurodevelopmental disorder. The implication of vitamin D in the etiopathogenesis of schizophrenia shows through the activation of cellular and inflammatory pathways. It is especially vitamin D deficiency that has been associated with schizophrenia. It is within this framework that this study aims to explore the relationship between vitamin D levels and the clinical characteristics in a cohort of Tunisian patients with schizophrenia. Methods A cross-sectional and retrospective descriptive study was conducted at the “F” psychiatry department at the Razi Hospital, Manouba over a twelve-month period from June 1st, 2015 to May 31st, 2016, including 80 patients with schizophrenia in period of clinical remission. The evaluation focused on sociodemographic and clinical characteristics. A dosage of vitamin D was performed. Results The patients had an average age of 42.5 years and 70% were male. The average vitamine D level was 10,57ng/ml ±5,9. 49% of patients had vitamin D insufficiency (between 10 and 30 ng/ml) and 51% had vitamin D deficiency (