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A comparison of outcomes between Canada and the United States in patients recovering from hip fracture repair: secondary analysis of the FOCUS trial

Abstract Objective To determine if adjusted mortality, walking ability or return home differed after hip fracture surgery between Canada and the USA. Design Secondary analysis of the Functional Outcomes in Cardiovascular Patients Undergoing Surgical Hip Fracture Repair (FOCUS) trial data. Setting Da...

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Published in:International journal for quality in health care 2018-03, Vol.30 (2), p.97-103
Main Authors: BEAUPRE, LAUREN A., WAI, EUGENE K., HOOVER, DONALD R., NOVECK, HELAINE, ROFFEY, DARREN M., COOK, DONALD R., MAGAZINER, JAY S., CARSON, JEFFREY L.
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cited_by cdi_FETCH-LOGICAL-c442t-cd5bc5145da8b03a48787c4d0359bbecd38134b25caa8c4ffa04ee41aaedc5eb3
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container_title International journal for quality in health care
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creator BEAUPRE, LAUREN A.
WAI, EUGENE K.
HOOVER, DONALD R.
NOVECK, HELAINE
ROFFEY, DARREN M.
COOK, DONALD R.
MAGAZINER, JAY S.
CARSON, JEFFREY L.
description Abstract Objective To determine if adjusted mortality, walking ability or return home differed after hip fracture surgery between Canada and the USA. Design Secondary analysis of the Functional Outcomes in Cardiovascular Patients Undergoing Surgical Hip Fracture Repair (FOCUS) trial data. Setting Data were collected from 47 American and Canadian hospitals. Participants Overall, 2016 subjects with a hip fracture (USA = 1222 (60.6%); Canada = 794 (39.4%)) were randomized to a liberal or restrictive transfusion strategy. Subjects were 50 years and older, with cardiovascular disease and/or risk factors and hemoglobin
doi_str_mv 10.1093/intqhc/mzx199
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Design Secondary analysis of the Functional Outcomes in Cardiovascular Patients Undergoing Surgical Hip Fracture Repair (FOCUS) trial data. Setting Data were collected from 47 American and Canadian hospitals. Participants Overall, 2016 subjects with a hip fracture (USA = 1222 (60.6%); Canada = 794 (39.4%)) were randomized to a liberal or restrictive transfusion strategy. Subjects were 50 years and older, with cardiovascular disease and/or risk factors and hemoglobin &lt;100 g/L within 3 days post-surgery. The average age was 82 years and 1527(76%) subjects were females. Intervention Demographics, health status and health services data were collected up to 60 days post-surgery and mortality to a median of 3 years post-surgery. Main outcomes Mortality, inability to walk and return home. Results US subjects had higher adjusted mortality than Canadians at 30 days (odds ratio = 1.78; 95% confidence interval: 1.09–2.90), 60 days (1.53; 1.02–2.29) and up to 3 years (hazard ratio = 1.25; 1.07–1.45). There were no differences in adjusted outcomes for walking ability or return home at 30 or 60 days post-surgery. Median hospital length of stay was longer (P &lt; 0.0001) in Canada (9 days; interquartile range: 5–18 days) than the US (3 days; 2–5 days). US subjects (52.9%) were more likely than Canadians (16.8%) to be discharged to nursing homes for rehabilitation (P &lt; 0.001). Conclusions Adjusted survival favored Canadians post hip fracture while walking ability and return home were not different between countries. The reason(s) for mortality differences warrant further investigation.</description><identifier>ISSN: 1353-4505</identifier><identifier>EISSN: 1464-3677</identifier><identifier>DOI: 10.1093/intqhc/mzx199</identifier><identifier>PMID: 29385446</identifier><language>eng</language><publisher>England: Oxford University Press</publisher><subject>Aged ; Aged, 80 and over ; Blood Transfusion - statistics &amp; numerical data ; Canada - epidemiology ; Female ; Hip Fractures - mortality ; Hip Fractures - rehabilitation ; Hip Fractures - surgery ; Humans ; Length of Stay - statistics &amp; numerical data ; Male ; Middle Aged ; Nursing Homes - statistics &amp; numerical data ; Postoperative Care ; Recovery of Function ; Risk Factors ; United States - epidemiology ; Walking</subject><ispartof>International journal for quality in health care, 2018-03, Vol.30 (2), p.97-103</ispartof><rights>The Author(s) 2018</rights><rights>The Author(s) 2018. Published by Oxford University Press in association with the International Society for Quality in Health Care. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com 2018</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c442t-cd5bc5145da8b03a48787c4d0359bbecd38134b25caa8c4ffa04ee41aaedc5eb3</citedby><cites>FETCH-LOGICAL-c442t-cd5bc5145da8b03a48787c4d0359bbecd38134b25caa8c4ffa04ee41aaedc5eb3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/48519814$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/48519814$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>230,314,780,784,885,1603,27923,27924,58237,58470</link.rule.ids><linktorsrc>$$Uhttps://dx.doi.org/10.1093/intqhc/mzx199$$EView_record_in_Oxford_University_Press$$FView_record_in_$$GOxford_University_Press</linktorsrc><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29385446$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>BEAUPRE, LAUREN A.</creatorcontrib><creatorcontrib>WAI, EUGENE K.</creatorcontrib><creatorcontrib>HOOVER, DONALD R.</creatorcontrib><creatorcontrib>NOVECK, HELAINE</creatorcontrib><creatorcontrib>ROFFEY, DARREN M.</creatorcontrib><creatorcontrib>COOK, DONALD R.</creatorcontrib><creatorcontrib>MAGAZINER, JAY S.</creatorcontrib><creatorcontrib>CARSON, JEFFREY L.</creatorcontrib><title>A comparison of outcomes between Canada and the United States in patients recovering from hip fracture repair: secondary analysis of the FOCUS trial</title><title>International journal for quality in health care</title><addtitle>Int J Qual Health Care</addtitle><description>Abstract Objective To determine if adjusted mortality, walking ability or return home differed after hip fracture surgery between Canada and the USA. Design Secondary analysis of the Functional Outcomes in Cardiovascular Patients Undergoing Surgical Hip Fracture Repair (FOCUS) trial data. Setting Data were collected from 47 American and Canadian hospitals. Participants Overall, 2016 subjects with a hip fracture (USA = 1222 (60.6%); Canada = 794 (39.4%)) were randomized to a liberal or restrictive transfusion strategy. Subjects were 50 years and older, with cardiovascular disease and/or risk factors and hemoglobin &lt;100 g/L within 3 days post-surgery. The average age was 82 years and 1527(76%) subjects were females. Intervention Demographics, health status and health services data were collected up to 60 days post-surgery and mortality to a median of 3 years post-surgery. Main outcomes Mortality, inability to walk and return home. Results US subjects had higher adjusted mortality than Canadians at 30 days (odds ratio = 1.78; 95% confidence interval: 1.09–2.90), 60 days (1.53; 1.02–2.29) and up to 3 years (hazard ratio = 1.25; 1.07–1.45). There were no differences in adjusted outcomes for walking ability or return home at 30 or 60 days post-surgery. Median hospital length of stay was longer (P &lt; 0.0001) in Canada (9 days; interquartile range: 5–18 days) than the US (3 days; 2–5 days). US subjects (52.9%) were more likely than Canadians (16.8%) to be discharged to nursing homes for rehabilitation (P &lt; 0.001). Conclusions Adjusted survival favored Canadians post hip fracture while walking ability and return home were not different between countries. The reason(s) for mortality differences warrant further investigation.</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Blood Transfusion - statistics &amp; numerical data</subject><subject>Canada - epidemiology</subject><subject>Female</subject><subject>Hip Fractures - mortality</subject><subject>Hip Fractures - rehabilitation</subject><subject>Hip Fractures - surgery</subject><subject>Humans</subject><subject>Length of Stay - statistics &amp; numerical data</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Nursing Homes - statistics &amp; numerical data</subject><subject>Postoperative Care</subject><subject>Recovery of Function</subject><subject>Risk Factors</subject><subject>United States - epidemiology</subject><subject>Walking</subject><issn>1353-4505</issn><issn>1464-3677</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><recordid>eNqFkc1P3DAQxa2KqlDg2CPIx15S7LWdOBcktOqXhNRDy9maOBPWaGMH2-Hrr8codNueeprRzE9vnuYR8oGzT5y14sz5fLuxZ-PTA2_bN-SAy1pWom6avdILJSqpmNon71O6YYzXQtXvyP6qFVpJWR-Q8YLaME4QXQqehoGGOZcBJtphvkf0dA0eeqDge5o3SK-8y9jTnxlygZynE2SHPica0YY7jM5f0yGGkW7cVBqweY5YlhO4eETeDrBNePxaD8nVl8-_1t-qyx9fv68vLisr5SpXtledVVyqHnTHBEjd6MbKngnVdh3aXmguZLdSFkBbOQzAJKLkANhbhZ04JOeL7jR3Y5kVfxG2ZopuhPhoAjjz78a7jbkOd0bplulaFIGPrwIx3M6YshldsrjdgscwJ1N-LYSum9ULWi2ojSGliMPuDGfmJSKzRGSWiAp_-re3Hf07kz-3wzz9V-tkQW9SDnEHS614q7kUz77kqvo</recordid><startdate>20180301</startdate><enddate>20180301</enddate><creator>BEAUPRE, LAUREN A.</creator><creator>WAI, EUGENE K.</creator><creator>HOOVER, DONALD R.</creator><creator>NOVECK, HELAINE</creator><creator>ROFFEY, DARREN M.</creator><creator>COOK, DONALD R.</creator><creator>MAGAZINER, JAY S.</creator><creator>CARSON, JEFFREY L.</creator><general>Oxford University Press</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20180301</creationdate><title>A comparison of outcomes between Canada and the United States in patients recovering from hip fracture repair</title><author>BEAUPRE, LAUREN A. ; WAI, EUGENE K. ; HOOVER, DONALD R. ; NOVECK, HELAINE ; ROFFEY, DARREN M. ; COOK, DONALD R. ; MAGAZINER, JAY S. ; CARSON, JEFFREY L.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c442t-cd5bc5145da8b03a48787c4d0359bbecd38134b25caa8c4ffa04ee41aaedc5eb3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Blood Transfusion - statistics &amp; numerical data</topic><topic>Canada - epidemiology</topic><topic>Female</topic><topic>Hip Fractures - mortality</topic><topic>Hip Fractures - rehabilitation</topic><topic>Hip Fractures - surgery</topic><topic>Humans</topic><topic>Length of Stay - statistics &amp; numerical data</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Nursing Homes - statistics &amp; numerical data</topic><topic>Postoperative Care</topic><topic>Recovery of Function</topic><topic>Risk Factors</topic><topic>United States - epidemiology</topic><topic>Walking</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>BEAUPRE, LAUREN A.</creatorcontrib><creatorcontrib>WAI, EUGENE K.</creatorcontrib><creatorcontrib>HOOVER, DONALD R.</creatorcontrib><creatorcontrib>NOVECK, HELAINE</creatorcontrib><creatorcontrib>ROFFEY, DARREN M.</creatorcontrib><creatorcontrib>COOK, DONALD R.</creatorcontrib><creatorcontrib>MAGAZINER, JAY S.</creatorcontrib><creatorcontrib>CARSON, JEFFREY L.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>International journal for quality in health care</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>BEAUPRE, LAUREN A.</au><au>WAI, EUGENE K.</au><au>HOOVER, DONALD R.</au><au>NOVECK, HELAINE</au><au>ROFFEY, DARREN M.</au><au>COOK, DONALD R.</au><au>MAGAZINER, JAY S.</au><au>CARSON, JEFFREY L.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A comparison of outcomes between Canada and the United States in patients recovering from hip fracture repair: secondary analysis of the FOCUS trial</atitle><jtitle>International journal for quality in health care</jtitle><addtitle>Int J Qual Health Care</addtitle><date>2018-03-01</date><risdate>2018</risdate><volume>30</volume><issue>2</issue><spage>97</spage><epage>103</epage><pages>97-103</pages><issn>1353-4505</issn><eissn>1464-3677</eissn><abstract>Abstract Objective To determine if adjusted mortality, walking ability or return home differed after hip fracture surgery between Canada and the USA. Design Secondary analysis of the Functional Outcomes in Cardiovascular Patients Undergoing Surgical Hip Fracture Repair (FOCUS) trial data. Setting Data were collected from 47 American and Canadian hospitals. Participants Overall, 2016 subjects with a hip fracture (USA = 1222 (60.6%); Canada = 794 (39.4%)) were randomized to a liberal or restrictive transfusion strategy. Subjects were 50 years and older, with cardiovascular disease and/or risk factors and hemoglobin &lt;100 g/L within 3 days post-surgery. The average age was 82 years and 1527(76%) subjects were females. Intervention Demographics, health status and health services data were collected up to 60 days post-surgery and mortality to a median of 3 years post-surgery. Main outcomes Mortality, inability to walk and return home. Results US subjects had higher adjusted mortality than Canadians at 30 days (odds ratio = 1.78; 95% confidence interval: 1.09–2.90), 60 days (1.53; 1.02–2.29) and up to 3 years (hazard ratio = 1.25; 1.07–1.45). There were no differences in adjusted outcomes for walking ability or return home at 30 or 60 days post-surgery. Median hospital length of stay was longer (P &lt; 0.0001) in Canada (9 days; interquartile range: 5–18 days) than the US (3 days; 2–5 days). US subjects (52.9%) were more likely than Canadians (16.8%) to be discharged to nursing homes for rehabilitation (P &lt; 0.001). Conclusions Adjusted survival favored Canadians post hip fracture while walking ability and return home were not different between countries. The reason(s) for mortality differences warrant further investigation.</abstract><cop>England</cop><pub>Oxford University Press</pub><pmid>29385446</pmid><doi>10.1093/intqhc/mzx199</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record>
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identifier ISSN: 1353-4505
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subjects Aged
Aged, 80 and over
Blood Transfusion - statistics & numerical data
Canada - epidemiology
Female
Hip Fractures - mortality
Hip Fractures - rehabilitation
Hip Fractures - surgery
Humans
Length of Stay - statistics & numerical data
Male
Middle Aged
Nursing Homes - statistics & numerical data
Postoperative Care
Recovery of Function
Risk Factors
United States - epidemiology
Walking
title A comparison of outcomes between Canada and the United States in patients recovering from hip fracture repair: secondary analysis of the FOCUS trial
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