Metabolic syndrome and its components with neuron-specific enolase: a cross-sectional study in large health check-up population in China

ObjectiveThis study was aimed at investigating the relationship between neuron-specific enolase (NSE) and components of metabolic syndrome (MS).DesignCross-sectional study.SettingChinese health check-up population.Participants40 684 health check-up people were enrolled in this study from year 2014 t...

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Bibliographic Details
Published in:BMJ open 2018-04, Vol.8 (4), p.e020899-e020899
Main Authors: Wang, Shu-Yi, Zha, Xiao-Juan, Zhu, Xin-Ying, Li, Wen-Bo, Ma, Jun, Wu, Ze-Wei, Wu, Huan, Jiang, Ming-Fei, Wen, Yu-Feng
Format: Article
Language:English
Subjects:
Archives & records
Atherosclerosis
Blood pressure
Body mass index
Brain damage
Brain diseases
Cancer
Cholesterol
Cross-sectional studies
Diabetes
Disease
Epidemiology
Hospitals
Hyperglycemia
Hypertension
Lipoproteins
Metabolic syndrome
Population
Public Health
Stroke
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Summary:ObjectiveThis study was aimed at investigating the relationship between neuron-specific enolase (NSE) and components of metabolic syndrome (MS).DesignCross-sectional study.SettingChinese health check-up population.Participants40 684 health check-up people were enrolled in this study from year 2014 to 2016.Main outcome measuresOR and coefficient for MS.ResultsThe percentage of abnormal NSE and MS was 26.85% and 8.85%, respectively. There were significant differences in sex, body mass index, drinking habit, triglycerides (TGs), high-density lipoprotein cholesterol (HDL-C), blood pressure and MS between low-NSE and high-NSE groups. In logistic regression analysis, elevated NSE was present in MS, higher body mass index, hypertriglyceridaemia, hypertension and low-HDL groups. Stepwise linear analysis showed a negative correlation between NSE and fasting blood glucose (FBG) (
ISSN:2044-6055
2044-6055
DOI:10.1136/bmjopen-2017-020899