Normal delivery following resection of an androgen-secreting adrenal carcinoma

A 31-year-old female presented to a gynecological clinic complaining of amenorrhea and virilism over a 2-month period. Blood tests revealed high serum total testosterone and free testosterone levels. A left adrenal tumor was identified following computed tomography and she was referred to our clinic...

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Bibliographic Details
Published in:Reproductive medicine and biology 2011-03, Vol.10 (1), p.55-58
Main Authors: Amano, Toshiyasu, Imao, Tetsuya, Seki, Masaya, Takemae, Katsurou, Yamauchi, Keishi, Hata, Satoru
Format: Article
Language:English
Subjects:
Adrenal cancer
Adrenalectomy
Amenorrhea
Androgens
Androgen‐secreting
Cancer
Carcinoma
Case Report
Computed tomography
Delivery
Gynecology
Laparoscopy
Literature reviews
Medicine
Medicine & Public Health
Menstruation
Pregnancy
Reproductive Medicine
Testosterone
Tumors
Urology
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Summary:A 31-year-old female presented to a gynecological clinic complaining of amenorrhea and virilism over a 2-month period. Blood tests revealed high serum total testosterone and free testosterone levels. A left adrenal tumor was identified following computed tomography and she was referred to our clinic where a laparoscopic left adrenalectomy was performed. The tumor weighed 98 g and the pathological diagnosis according to Weiss’ criteria was adrenocortical carcinoma. The post-operative course was uneventful; her serum free testosterone level normalized and regular menstruation was observed 1 month post-operatively. The patient became pregnant 1 year later, resulting in the normal delivery of a girl.
ISSN:1445-5781
1447-0578
DOI:10.1007/s12522-010-0071-4