Diverticular Disease-associated Colitis: What Do We Know? A Review of Literature

Diverticular disease (DD) is a leading cause of hospitalizations in developed countries affecting 30-50% of individuals older than 60 years. Identified as a distinct entity since 1980, diverticular disease-associated colitis (DAC) describes the occurrence of mucosal inflammation in a colon segment a...

Full description

Saved in:
Bibliographic Details
Published in:Curēus (Palo Alto, CA) CA), 2018-02, Vol.10 (2), p.e2224-e2224
Main Authors: Haddad, Fady G, El Bitar, Sandy, Al Moussawi, Hassan, Chang, Qing, Deeb, Liliane
Format: Article
Language:English
Subjects:
Antibiotics
Appendicitis
Colon
Endoscopy
Gastroenterology
Granulomas
Hospitals
Hypotheses
Inflammation
Inflammatory bowel disease
Oncology
Pathology
Surgery
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Diverticular disease (DD) is a leading cause of hospitalizations in developed countries affecting 30-50% of individuals older than 60 years. Identified as a distinct entity since 1980, diverticular disease-associated colitis (DAC) describes the occurrence of mucosal inflammation in a colon segment affected with DD with relative sparing of the rectum and proximal colon. Its prevalence is suggested around 1.3-3.8%. Pathogenesis is multifactorial with multiple reports noting clinicopathological overlap between DAC and inflammatory bowel disease (IBD) especially in patients with granulomatous colitis. In this setting, caution should be exercised to avoid an inappropriate diagnosis of IBD. Recurrence rates and long-term outcomes of DAC are not well defined and could range from a benign course to an overt IBD. More studies are needed in order to further characterize this entity.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.2224