Detection of Human Papillomavirus Type 16 DNA and Papillomavirus Genus‐specific Antigens in Vulva and Cervix from Patients with Bowenoid Papulosis

The warty disordered lesions of the vulva in three female patients were diagnosed as Bowenoid papulosis on the basis of clinical and histopathological findings. In all three vulvar lesions, human Papillomavirus type 16 (HPV 16) DNA was identified hy Southern blot hybridization and Papillomavirus gen...

Full description

Saved in:
Bibliographic Details
Published in:Cancer science 1989-01, Vol.80 (1), p.19-23
Main Authors: Sugase, Motoyasu, Moriyama, Shin‐ichi, Hata, Satoru, Matsukura, Toshihiko
Format: Article
Language:English
Subjects:
Adult
Antigens
Antigens, Viral - analysis
Biological and medical sciences
Bowenoid papulosis
Cervix
Cervix Uteri - microbiology
Cervix Uteri - pathology
Deoxyribonucleic acid
DNA
DNA, Viral - analysis
Female
Female genital diseases
Female genital tract
Gynecology. Andrology. Obstetrics
HPV 16
Human papillomavirus
Humans
Hybridization
Lesions
Medical sciences
Middle Aged
Papillomaviridae - genetics
Papillomaviridae - immunology
Tumors
Uterine Cervical Neoplasms - pathology
Uterus
Vulva
Vulva - microbiology
Vulva - pathology
Vulvar Diseases - microbiology
Vulvar Diseases - pathology
Warts - microbiology
Warts - pathology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The warty disordered lesions of the vulva in three female patients were diagnosed as Bowenoid papulosis on the basis of clinical and histopathological findings. In all three vulvar lesions, human Papillomavirus type 16 (HPV 16) DNA was identified hy Southern blot hybridization and Papillomavirus genus‐specific (PGS) antigen was detected in one case immunohistochemically. Furthermore, colposcopic examination revealed the presence of abnormal uterine cervical lesions in two cases. They were found to be intraepithelial neoplasia which harbored HPV 16 DNA and were positive for PGS antigen.
ISSN:0910-5050
1347-9032
1349-7006
1876-4673
DOI:10.1111/j.1349-7006.1989.tb02239.x