Calcific myonecrosis mimicking soft tissue sarcoma: A case report

Calcific myonecrosis is a rare soft tissue condition. The first case was reported in 1960, however, the precise pathophysiology of calcific myonecrosis remains unclear. The disease was thought to arise from compartment syndrome within a confined space resulting in necrosis and fibrosis, subsequent r...

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Bibliographic Details
Published in:Oncology letters 2018-05, Vol.15 (5), p.7909-7913
Main Authors: Ukon, Yuichiro, Tanaka, Takaaki, Nagata, Shigenori, Hagizawa, Hiroki, Imura, Yoshinori, Tamiya, Hironari, Oshima, Kazuya, Naka, Norifumi, Aoki, Yasuaki, Kuratsu, Shigeyuki
Format: Article
Language:English
Subjects:
Biopsy
Calcification
Care and treatment
Case reports
Case studies
Diagnosis
Gangrene
Medical imaging
Myonecrosis
Sarcoma
Sinuses
Tissues
Tumors
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Summary:Calcific myonecrosis is a rare soft tissue condition. The first case was reported in 1960, however, the precise pathophysiology of calcific myonecrosis remains unclear. The disease was thought to arise from compartment syndrome within a confined space resulting in necrosis and fibrosis, subsequent repeated intralesional hemorrhage, mass enlargement and calcification. Several previous reports have described calcific myonecrosis, which include the formation of calcific myonecrosis after a prolonged period of post trauma. Notably, calcific myonecrosis has typically been described in the lower legs and characteristic imaging findings have been indicated. Furthermore, surgical intervention carries a high risk of complications. In the present case report 2 cases of calcific myonecrosis that occurred after a prolonged period of time following a traumatic event that impacted the lower leg were reported. CT images revealed disruption of calcified fascia and disease expansion into the outside of the fascia. Previous reports have implied that there is late focal enlargement of calcific myonecrosis following earlier enlargement, which may be caused by herniation through muscle fascia. However, no previous publications have focused on images for evidence of late local enlargement. To the best of our knowledge, this is the first report focusing on fascial herniation of calcific myonecrosis using images. Analysis of this feature using images may aid clinicians to differentiate calcific myonecrosis from malignancies.
ISSN:1792-1074
1792-1082
DOI:10.3892/ol.2018.8320