Chronic fatigue: is it endocrinology?

Fatigue and stress-related illnesses often become diagnoses of exclusion after extensive investigation. ‘Tired all the time’ is a frequent reason for referral to the endocrine clinic, the implicit question being – is there a subtle endocrine pathology contributing to the patient's symptoms? Oft...

Full description

Saved in:
Bibliographic Details
Published in:Clinical medicine (London, England) England), 2009-02, Vol.9 (1), p.34-38
Main Authors: Evans, Kate M, Flanagan, Daniel E, Wilkin, Terence J
Format: Article
Language:English
Subjects:
Original Papers
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Fatigue and stress-related illnesses often become diagnoses of exclusion after extensive investigation. ‘Tired all the time’ is a frequent reason for referral to the endocrine clinic, the implicit question being – is there a subtle endocrine pathology contributing to the patient's symptoms? Often initial assessment suggests not but there are no clear data to address the question of whether overt pathology will develop in the future. This study observed outcomes after five years in 101 consecutive and unselected referrals to secondary care for ‘fatigue? cause’, where initial assessment did not suggest treatable endocrine pathology. The findings suggest that the clinical diagnosis of fatigue, based on history and tests to exclude anaemia, hypothyroidism and diabetes, is secure: these patients do not subsequently demonstrate excess morbidity and mortality, and their presenting symptoms are not early features of significant endocrine pathology.
ISSN:1470-2118
1473-4893
DOI:10.7861/clinmedicine.9-1-34