Nutraceuticals for Skin Care: A Comprehensive Review of Human Clinical Studies

The skin is the body's largest organ, it participates in sensitivity and offers protection against microorganisms, chemicals and ultraviolet (UV) radiation. Consequently, the skin may suffer alterations such as photo-ageing, immune dysfunction and inflammation which may significantly affect hum...

Full description

Saved in:
Bibliographic Details
Published in:Nutrients 2018-03, Vol.10 (4), p.403
Main Authors: Pérez-Sánchez, Almudena, Barrajón-Catalán, Enrique, Herranz-López, María, Micol, Vicente
Format: Article
Language:English
Subjects:
Aging
Biological effects
Carotenoids
Clinical trials
dietary supplements
Functional foods & nutraceuticals
human health
inflammation
Ingredients
Microorganisms
Oligosaccharides
Peptides
photoaging
Polyphenols
Polyunsaturated fatty acids
Review
Skin
skin diseases
Ultraviolet radiation
Vitamins
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The skin is the body's largest organ, it participates in sensitivity and offers protection against microorganisms, chemicals and ultraviolet (UV) radiation. Consequently, the skin may suffer alterations such as photo-ageing, immune dysfunction and inflammation which may significantly affect human health. Nutraceuticals represent a promising strategy for preventing, delaying, or minimising premature ageing of the skin and also to alleviate certain skin disorders. Among them, bioactive peptides and oligosaccharides, plant polyphenols, carotenoids, vitamins and polyunsaturated fatty acids are the most widely used ingredients. Supplementation with these products has shown evidence of having an effect on the signs of ageing and protection against UV radiation ageing in several human trials. In this review, the most relevant human studies on skin nutraceuticals are evaluated and the statistical resolution, biological relevance of their results, and, the trial protocols are discussed. In conclusion, quality and rigorousness of the trials must be improved to build credible scientific evidence for skin nutraceuticals and to establish a cause-effect relationship between the ingredients the beneficial effects for the skin.
ISSN:2072-6643
2072-6643
DOI:10.3390/nu10040403