Measuring Loop Gain via Home Sleep Testing in Patients with Obstructive Sleep Apnea

Measuring loop gain has traditionally required the use of specialized equipment and laborintensive techniques (5); however, recently developed methods can determine loop gain from polysomnography (PSG) using a modelfitting technique (6). Because clinical testing for OSA is shifting to home sleep tes...

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Bibliographic Details
Published in:American journal of respiratory and critical care medicine 2018-05, Vol.197 (10), p.1353-1355
Main Authors: Orr, Jeremy E, Sands, Scott A, Edwards, Bradley A, Deyoung, Pamela N, Deacon, Naomi, Jen, Rachel, Li, Yanru, Owens, Robert L, Malhotra, Atul
Format: Article
Language:English
Subjects:
Correspondence
Physiology
Sleep apnea
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Summary:Measuring loop gain has traditionally required the use of specialized equipment and laborintensive techniques (5); however, recently developed methods can determine loop gain from polysomnography (PSG) using a modelfitting technique (6). Because clinical testing for OSA is shifting to home sleep testing (HST), our aim in this study was to determine whether we could estimate loop gain using this limited dataset, which might facilitate personalized OSA treatment in clinical practice. The research was approved by the institutional review board (#141272 and #150465), and the subjects provided written informed consent. [...]studies were performed on different nights. [...]in accordance with our study design, we did not perform more traditional loop gain assessments (e.g., CPAP drops and proportional assist ventilation).
ISSN:1073-449X
1535-4970
DOI:10.1164/rccm.201707-1357LE