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Nipah Virus Infection
Nipah virus, a paramyxovirus related to Hendra virus, first emerged in Malaysia in 1998. Clinical presentation ranges from asymptomatic infection to fatal encephalitis. Malaysia has had no more cases since 1999, but outbreaks continue to occur in Bangladesh and India. In the Malaysia-Singapore outbr...
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Published in: | Journal of clinical microbiology 2018-06, Vol.56 (6) |
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container_title | Journal of clinical microbiology |
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creator | Ang, Brenda S P Lim, Tchoyoson C C Wang, Linfa |
description | Nipah virus, a paramyxovirus related to Hendra virus, first emerged in Malaysia in 1998. Clinical presentation ranges from asymptomatic infection to fatal encephalitis. Malaysia has had no more cases since 1999, but outbreaks continue to occur in Bangladesh and India. In the Malaysia-Singapore outbreak, transmission occurred primarily through contact with pigs, whereas in Bangladesh and India, it is associated with ingestion of contaminated date palm sap and human-to-human transmission. Bats are the main reservoir for this virus, which can cause disease in humans and animals. There are currently no effective therapeutics, and supportive care and prevention are the mainstays of management. |
doi_str_mv | 10.1128/JCM.01875-17 |
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Clinical presentation ranges from asymptomatic infection to fatal encephalitis. Malaysia has had no more cases since 1999, but outbreaks continue to occur in Bangladesh and India. In the Malaysia-Singapore outbreak, transmission occurred primarily through contact with pigs, whereas in Bangladesh and India, it is associated with ingestion of contaminated date palm sap and human-to-human transmission. Bats are the main reservoir for this virus, which can cause disease in humans and animals. There are currently no effective therapeutics, and supportive care and prevention are the mainstays of management.</description><identifier>ISSN: 0095-1137</identifier><identifier>EISSN: 1098-660X</identifier><identifier>DOI: 10.1128/JCM.01875-17</identifier><identifier>PMID: 29643201</identifier><language>eng</language><publisher>United States: American Society for Microbiology</publisher><subject>Abattoirs ; Animals ; Bangladesh - epidemiology ; Chiroptera - virology ; Disease Outbreaks ; Disease Reservoirs - virology ; Encephalitis - epidemiology ; Encephalitis - virology ; Henipavirus Infections - epidemiology ; Henipavirus Infections - history ; Henipavirus Infections - transmission ; History, 20th Century ; History, 21st Century ; Humans ; India - epidemiology ; Malaysia - epidemiology ; Minireview ; Nipah Virus - genetics ; Phoeniceae - virology ; Singapore - epidemiology ; Swine - virology</subject><ispartof>Journal of clinical microbiology, 2018-06, Vol.56 (6)</ispartof><rights>Copyright © 2018 American Society for Microbiology.</rights><rights>Copyright © 2018 American Society for Microbiology. 2018 American Society for Microbiology</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c427t-fe3a29ae91acd15b7d0fe70e76be813c84ecd30f34c2b99907efa7bafa5c033</citedby><cites>FETCH-LOGICAL-c427t-fe3a29ae91acd15b7d0fe70e76be813c84ecd30f34c2b99907efa7bafa5c033</cites><orcidid>0000-0003-2752-0535</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5971524/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5971524/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,3186,27922,27923,53789,53791</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29643201$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Kraft, Colleen Suzanne</contributor><creatorcontrib>Ang, Brenda S P</creatorcontrib><creatorcontrib>Lim, Tchoyoson C C</creatorcontrib><creatorcontrib>Wang, Linfa</creatorcontrib><title>Nipah Virus Infection</title><title>Journal of clinical microbiology</title><addtitle>J Clin Microbiol</addtitle><description>Nipah virus, a paramyxovirus related to Hendra virus, first emerged in Malaysia in 1998. Clinical presentation ranges from asymptomatic infection to fatal encephalitis. Malaysia has had no more cases since 1999, but outbreaks continue to occur in Bangladesh and India. In the Malaysia-Singapore outbreak, transmission occurred primarily through contact with pigs, whereas in Bangladesh and India, it is associated with ingestion of contaminated date palm sap and human-to-human transmission. Bats are the main reservoir for this virus, which can cause disease in humans and animals. There are currently no effective therapeutics, and supportive care and prevention are the mainstays of management.</description><subject>Abattoirs</subject><subject>Animals</subject><subject>Bangladesh - epidemiology</subject><subject>Chiroptera - virology</subject><subject>Disease Outbreaks</subject><subject>Disease Reservoirs - virology</subject><subject>Encephalitis - epidemiology</subject><subject>Encephalitis - virology</subject><subject>Henipavirus Infections - epidemiology</subject><subject>Henipavirus Infections - history</subject><subject>Henipavirus Infections - transmission</subject><subject>History, 20th Century</subject><subject>History, 21st Century</subject><subject>Humans</subject><subject>India - epidemiology</subject><subject>Malaysia - epidemiology</subject><subject>Minireview</subject><subject>Nipah Virus - genetics</subject><subject>Phoeniceae - virology</subject><subject>Singapore - epidemiology</subject><subject>Swine - virology</subject><issn>0095-1137</issn><issn>1098-660X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><recordid>eNpVkE1Lw0AQhhdRbK3e9CoePZg6s7vJZi-CFD8qVQ-KeFs2m1kbaZOaTQT_vamtRU8D7zy8MzyMHSIMEXl6fje6HwKmKo5QbbE-gk6jJIHXbdYH0F2KQvXYXgjvAChlHO-yHteJFBywz44eioWdnrwUdRtOxqUn1xRVuc92vJ0FOljPAXu6vnoe3UaTx5vx6HISOclVE3kSlmtLGq3LMc5UDp4UkEoySlG4VJLLBXghHc-01qDIW5VZb2MHQgzYxap10WZzyh2VTW1nZlEXc1t_mcoW5v-mLKbmrfo0sVYYc9kVnK4L6uqjpdCYeREczWa2pKoNhgOXMlEqWaJnK9TVVQg1-c0ZBLP0aDqP5sejQdXhx39f28C_4sQ3YzJt3w</recordid><startdate>20180601</startdate><enddate>20180601</enddate><creator>Ang, Brenda S P</creator><creator>Lim, Tchoyoson C C</creator><creator>Wang, Linfa</creator><general>American Society for Microbiology</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0003-2752-0535</orcidid></search><sort><creationdate>20180601</creationdate><title>Nipah Virus Infection</title><author>Ang, Brenda S P ; Lim, Tchoyoson C C ; Wang, Linfa</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c427t-fe3a29ae91acd15b7d0fe70e76be813c84ecd30f34c2b99907efa7bafa5c033</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Abattoirs</topic><topic>Animals</topic><topic>Bangladesh - epidemiology</topic><topic>Chiroptera - virology</topic><topic>Disease Outbreaks</topic><topic>Disease Reservoirs - virology</topic><topic>Encephalitis - epidemiology</topic><topic>Encephalitis - virology</topic><topic>Henipavirus Infections - epidemiology</topic><topic>Henipavirus Infections - history</topic><topic>Henipavirus Infections - transmission</topic><topic>History, 20th Century</topic><topic>History, 21st Century</topic><topic>Humans</topic><topic>India - epidemiology</topic><topic>Malaysia - epidemiology</topic><topic>Minireview</topic><topic>Nipah Virus - genetics</topic><topic>Phoeniceae - virology</topic><topic>Singapore - epidemiology</topic><topic>Swine - virology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ang, Brenda S P</creatorcontrib><creatorcontrib>Lim, Tchoyoson C C</creatorcontrib><creatorcontrib>Wang, Linfa</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of clinical microbiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ang, Brenda S P</au><au>Lim, Tchoyoson C C</au><au>Wang, Linfa</au><au>Kraft, Colleen Suzanne</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Nipah Virus Infection</atitle><jtitle>Journal of clinical microbiology</jtitle><addtitle>J Clin Microbiol</addtitle><date>2018-06-01</date><risdate>2018</risdate><volume>56</volume><issue>6</issue><issn>0095-1137</issn><eissn>1098-660X</eissn><abstract>Nipah virus, a paramyxovirus related to Hendra virus, first emerged in Malaysia in 1998. Clinical presentation ranges from asymptomatic infection to fatal encephalitis. Malaysia has had no more cases since 1999, but outbreaks continue to occur in Bangladesh and India. In the Malaysia-Singapore outbreak, transmission occurred primarily through contact with pigs, whereas in Bangladesh and India, it is associated with ingestion of contaminated date palm sap and human-to-human transmission. Bats are the main reservoir for this virus, which can cause disease in humans and animals. There are currently no effective therapeutics, and supportive care and prevention are the mainstays of management.</abstract><cop>United States</cop><pub>American Society for Microbiology</pub><pmid>29643201</pmid><doi>10.1128/JCM.01875-17</doi><orcidid>https://orcid.org/0000-0003-2752-0535</orcidid><oa>free_for_read</oa></addata></record> |
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source | American Society for Microbiology Journals; PubMed Central |
subjects | Abattoirs Animals Bangladesh - epidemiology Chiroptera - virology Disease Outbreaks Disease Reservoirs - virology Encephalitis - epidemiology Encephalitis - virology Henipavirus Infections - epidemiology Henipavirus Infections - history Henipavirus Infections - transmission History, 20th Century History, 21st Century Humans India - epidemiology Malaysia - epidemiology Minireview Nipah Virus - genetics Phoeniceae - virology Singapore - epidemiology Swine - virology |
title | Nipah Virus Infection |
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