Comparison between low disease activity or DAS remission as treatment target in patients with early active rheumatoid arthritis

ObjectivesTo compare outcomes of targeted treatment aimed at either low disease activity or remission in patients with early active rheumatoid arthritis (RA).MethodsFive-year outcomes were compared in 133 patients with early active RA (1987), starting with methotrexate, sulfasalazine and tapered hig...

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Published in:Rheumatic & musculoskeletal diseases open 2018, Vol.4 (1), p.e000649-e000649
Main Authors: Akdemir, Gülşah, Markusse, Iris M, Bergstra, Sytske Anne, Goekoop, Robbert J, Molenaar, Esmeralda T, van Groenendael, Johannes H L M, Kerstens, Pit J S M, Lems, Willem F, Huizinga, Tom W J, Allaart, Cornelia F
Format: Article
Language:English
Subjects:
Classification
Clinical trials
Drug dosages
Health risk assessment
Rheumatism
Rheumatoid Arthritis
Rheumatology
Studies
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Summary:ObjectivesTo compare outcomes of targeted treatment aimed at either low disease activity or remission in patients with early active rheumatoid arthritis (RA).MethodsFive-year outcomes were compared in 133 patients with early active RA (1987), starting with methotrexate, sulfasalazine and tapered high dose of prednisone (arm 3 of the BehandelStrategieën (Treatment Strategies for Rheumatoid Arthritis) (BeSt) study), targeted at Disease Activity Score (DAS) ≤2.4 (low disease activity), and 175 patients with early RA, starting methotrexate and tapered high dose of prednisone, targeted at DAS
ISSN:2056-5933
2056-5933
DOI:10.1136/rmdopen-2018-000649