Asthma and Seroconversion from Toxocara spp. Infection: Which Comes First?

The aim of this study was to estimate the incidence of seroconversion of Toxocara spp. infection and related variables. We conducted a cohort study of 77 children aged 2–12 years who had negative serology in a previous cross-sectional study. Univariate and bivariate analyses were performed to descri...

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Bibliographic Details
Published in:BioMed research international 2018-01, Vol.2018 (2018), p.1-6
Main Authors: Fialho, Paula Mayara Matos, Lescano, Susana Zevallos, Correa, Carlos Roberto Silveira
Format: Article
Language:English
Subjects:
Adsorption
Animals
Antibodies, Helminth - blood
Antigens
Ascaris
Ascaris suum
Asthma
Asthma - blood
Asthma - epidemiology
Asthma - etiology
Bivariate analysis
Child
Child, Preschool
Children
Children & youth
Dependent variables
Female
Humans
Hygiene
Hypotheses
Immunoglobulins
Immunology
Incidence
Independent variables
Infection
Infections
Laboratories
Male
Parasitology
Population
Regression analysis
Seroconversion
Serology
Studies
Toxocara
Toxocariasis
Toxocariasis - blood
Toxocariasis - complications
Toxocariasis - epidemiology
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Summary:The aim of this study was to estimate the incidence of seroconversion of Toxocara spp. infection and related variables. We conducted a cohort study of 77 children aged 2–12 years who had negative serology in a previous cross-sectional study. Univariate and bivariate analyses were performed to describe the cohort, using socioeconomic, behavioral, and health conditions as variables. Logistic regression analysis was performed using seroconversion as the dependent variable, and the remaining variables are treated as independent variables. Asthma was the only independent variable that showed an association with seroconversion, with an odds ratio = 3.57 (1.01–12.6). The incidence of seroconversion from Toxocara spp. infection in the children followed was 10.4 per 100 per year. Previous studies reporting an association of asthma with toxocariasis have only been carried out using cross-sectional studies. Therefore, this study is one of only a few describing the incidence of seroconversion from Toxocara spp. infection, which is relevant for understanding the burden of this parasite.
ISSN:2314-6133
2314-6141
DOI:10.1155/2018/4280792