Effect of heart rate and pacing mode on QRS fragmentation

Background The study was designed to investigate the effect of heart rate and pacing mode on QRS fragmentation (f‐QRS). Moreover, the usefulness of f‐QRS in distinguishing patients with impaired left ventricular ejection function (EF) and ventricular tachycardia (VT) from patients with normal EF was...

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Bibliographic Details
Published in:Journal of arrhythmia 2018-06, Vol.34 (3), p.267-273
Main Authors: Zagkli, Fani, Despotopoulos, Stefanos, Spiliotopoulos, Christos, Chiladakis, John
Format: Article
Language:English
Subjects:
Cardiomyopathy
Cardiovascular disease
Coronary vessels
Electrocardiography
Heart
Heart beat
Heart rate
left ventricular function
Medical research
Medicine, Experimental
Original
pacing
Patients
QRS fragmentation
Tachycardia
ventricular tachycardia
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Summary:Background The study was designed to investigate the effect of heart rate and pacing mode on QRS fragmentation (f‐QRS). Moreover, the usefulness of f‐QRS in distinguishing patients with impaired left ventricular ejection function (EF) and ventricular tachycardia (VT) from patients with normal EF was assessed. Methods Three hundred and six recipients, with dual‐chamber device, with intrinsic narrow or wide QRS complex and preserved atrioventricular conduction were grouped into normal‐EF or impaired‐EF VT. We analyzed intrinsic narrow f‐QRS and wide f‐QRS as well as ventricular‐paced f‐QRS following different heart rates (baseline, 100 bpm) and pacing modes. Results In the baseline state, overall, patients with impaired‐EF VT (35 ± 9%), compared to those with normal‐EF, had more f‐QRS (56% vs 27%, P 
ISSN:1880-4276
1883-2148
DOI:10.1002/joa3.12060