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Fat‐Free Mass and Skeletal Muscle Mass Five Years After Bariatric Surgery

Objective This study investigated changes in fat‐free mass (FFM) and skeletal muscle 5 years after surgery in participants from the Longitudinal Assessment of Bariatric Surgery‐2 trial. Methods A three‐compartment model assessed FFM, and whole‐body magnetic resonance imaging (MRI) quantified skeleta...

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Published in:Obesity (Silver Spring, Md.) Md.), 2018-07, Vol.26 (7), p.1130-1136
Main Authors: Davidson, Lance E., Yu, Wen, Goodpaster, Bret H., DeLany, James P., Widen, Elizabeth, Lemos, Thaisa, Strain, Gladys W., Pomp, Alfons, Courcoulas, Anita P., Lin, Susan, Janumala, Isaiah, Thornton, John C., Gallagher, Dympna
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Language:English
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Summary:Objective This study investigated changes in fat‐free mass (FFM) and skeletal muscle 5 years after surgery in participants from the Longitudinal Assessment of Bariatric Surgery‐2 trial. Methods A three‐compartment model assessed FFM, and whole‐body magnetic resonance imaging (MRI) quantified skeletal muscle mass prior to surgery (T0) and 1 year (T1), 2 years (T2), and 5 years (T5) postoperatively in 93 patients (85% female; 68% Caucasian; age 44.2 ± 11.6 years) who underwent gastric bypass (RYGB), sleeve gastrectomy, or adjustable gastric band. Repeated‐measures mixed models were used to analyze the data. Results Significant weight loss occurred across all surgical groups in females from T0 to T1. FFM loss from T0 to T1 was greater after RYGB (mean ± SE: −6.9 ± 0.6 kg) than adjustable gastric band (−3.5 ± 1.4 kg; P 
ISSN:1930-7381
1930-739X
DOI:10.1002/oby.22190