Prevalence and risk factors of latent tuberculosis among Korean healthcare workers using whole-blood interferon-γ release assay

Because healthcare workers (HCWs) are at high risk for tuberculosis (TB) infection, it is essential to research the prevalence of latent TB infection (LTBI) and to implement health interventions including early treatment of LTBI and TB infection control measures. The purpose of the study was to dete...

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Bibliographic Details
Published in:Scientific reports 2018-07, Vol.8 (1), p.10113-5, Article 10113
Main Authors: Yeon, Jeong Hwa, Seong, Hye, Hur, Ho, Park, Yoonseon, Kim, Young Ah, Park, Yoon Soo, Han, Chang Hoon, Lee, Sun Min, Seo, Jeong Hun, Kang, Jung Gu
Format: Article
Language:English
Subjects:
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692/700/3160
Diabetes mellitus
Disease control
Health care
Health promotion
Humanities and Social Sciences
Infections
Interferon
Medical personnel
multidisciplinary
Multivariate analysis
Patients
Risk factors
Science
Science (multidisciplinary)
Tuberculosis
Workers
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Summary:Because healthcare workers (HCWs) are at high risk for tuberculosis (TB) infection, it is essential to research the prevalence of latent TB infection (LTBI) and to implement health interventions including early treatment of LTBI and TB infection control measures. The purpose of the study was to determine the prevalence and risk factors for LTBI using interferon-γ release assay (IGRA) among HCWs in South Korea. The cross-sectional study was carried in the National Health Insurance Service Ilsan Hospital, which is a 740-bed general hospital, South Korea. HCWs who participated in this survey were required to complete a questionnaire and IGRA was performed. Of the 1,655 HCWs, 271 results were positive and the prevalence of LTBI was 16% (95% CI; 15–18%). In the multivariate analysis, age (OR; 2.201, 95% CI; 1.911–2.536, P 
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-018-28430-w