Morphological Study of Chitosan/Poly (Vinyl Alcohol) Nanofibers Prepared by Electrospinning, Collected on Reticulated Vitreous Carbon

• Published in: International journal of molecular sciences 2018-06, Vol.19 (6), p.1718
• Main Authors: Sanchez-Alvarado, Diana Isela, Guzmán-Pantoja, Javier, Páramo-García, Ulises, Maciel-Cerda, Alfredo, Martínez-Orozco, Reinaldo David, Vera-Graziano, Ricardo
• Format: Article
• Language: English
• Subjects: Alcohol; Carbon - chemistry; Chitosan; Chitosan - chemistry; Electric potential; Electrospinning; Fibers; Flow velocity; Morphology; Nanofibers; Nanofibers - chemistry; Nanofibers - ultrastructure; Nanotechnology - methods; Polyvinyl Alcohol - chemistry; Scanning electron microscopy; Sodium hydroxide; Solutions; Viscosity; Voltage
• ISSN: 1422-0067; 1661-6596; 1422-0067
• DOI: 10.3390/ijms19061718

In this work, chitosan (CS)/poly (vinyl alcohol) (PVA) nanofibers were prepared by using the electrospinning method. Different CS concentrations (0.5, 1, 2, and 3 wt %), maintaining the PVA concentration at 8 wt %, were tested. Likewise, the studied electrospinning experimental parameters were: syringe/collector distance, solution flow and voltage. Subsequently, the electrospun fibers were collected on a reticulated vitreous carbon (RVC) support for 0.25, 0.5, 1, 1.5, and 2 h. The morphology and diameter of the CS/PVA nanofibers were characterized by scanning electron microscopy (SEM), finding diameters in the order of 132 and 212 nm; the best results (uniform fibers) were obtained from the solution with 2 wt % of chitosan and a voltage, distance, and flow rate of 16 kV, 20 cm, and 0.13 mL/h, respectively. Afterwards, a treatment with an ethanolic NaOH solution was performed, observing a change in the fiber morphology and a diameter decrease (117 ± 9 nm).