Where do these guests come from? A diagnostic approach for metastatic lymph nodes

Objective: In cases presenting with lymphadenopathies (LAP) without a primary focus detected by simple radiological methods, the primary tumor can be diagnosed by a histopathological evaluation of the metastatic lymph nodes. We aimed to discuss the nonhematological malignancies presenting with lymph...

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Bibliographic Details
Published in:Turkish journal of surgery 2018-06, Vol.34 (2), p.131-136
Main Authors: Dere, Yelda, Ekmekci, Sumeyye, Celik, Serkan, Celik, Ozgür Ilhan, Dere, Ozcan, Karakus, Volkan
Format: Article
Language:English
Subjects:
Biopsy
Bladder cancer
Breast cancer
Family medical history
Females
Hematology
Hospitals
Kidney cancer
Lymphatic system
Medical diagnosis
Melanoma
Metastasis
NMR
Nuclear magnetic resonance
Original
Pathology
Skin cancer
Systematic review
Tumors
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Summary:Objective: In cases presenting with lymphadenopathies (LAP) without a primary focus detected by simple radiological methods, the primary tumor can be diagnosed by a histopathological evaluation of the metastatic lymph nodes. We aimed to discuss the nonhematological malignancies presenting with lymphadenopathies and the histopathological results for primary tumors. Material and Methods: In this retrospective study, cases diagnosed with metastasis in excisional lymph nodes between January 2013 and June 2016 were assessed for a histopathological diagnostic approach Results: Among 632 lymph node biopsies, a total of 21 cases, involving 12 male and 9 female patients with a mean age of 57.23 y (range, 33–92 y), of nonhematological solid tumors were included. The most common localizations of the involved lymph nodes were inguinal (n=8), axillary (n=6), cervical (n=4), and supraclavicular (n=3) region. The most common primary tumors were malignant melanoma (n=6), breast carcinoma (n=4), ovarian carcinoma (n=2), squamous cell carcinoma (n=2), and germ cell tumor (n=2). Others were papillary thyroid carcinoma, renal cell carcinoma, urothelial carcinoma, prostate adenocarcinoma, and endometrial adenocarcinoma. Conclusion: Nonhematological malignancies presenting with lymphadenopathies are one of the most complicated cases for clinicians. The histopathological evaluation of the excisional metastatic lymph node biopsies is an important method because of cost effectiveness and easy applicability.
ISSN:2564-6850
2564-7032
DOI:10.5152/turkjsurg.2018.3856