HIV knowledge trends during an era of rapid antiretroviral therapy scale‐up: an analysis of 33 sub‐Saharan African countries

• Published in: Journal of the International AIDS Society 2018-07, Vol.21 (7), p.e25169-n/a
• Main Authors: Chan, Brian T, Tsai, Alexander C
• Format: Article
• Language: English
• Subjects: 21st century; Acquired immune deficiency syndrome; Acquired Immunodeficiency Syndrome; Adolescent; Adult; Africa; Africa South of the Sahara; AIDS; Antiretroviral agents; Antiretroviral drugs; Control; Data analysis; Diagnosis; Disease transmission; Dosage and administration; Drug therapy; Female; Health Knowledge, Attitudes, Practice; Health surveys; HIV; HIV infections; HIV Infections - prevention & control; Human immunodeficiency virus; Humans; Knowledge; Male; Medical tests; Patient outcomes; Population; Prevention; Stigma; Surveys and Questionnaires; Trends; Young Adult
• ISSN: 1758-2652; 1758-2652
• DOI: 10.1002/jia2.25169

Introduction Population‐level improvements in knowledge about HIV may reduce the stigma attached to HIV and ensure maximal uptake of HIV prevention initiatives. The extent to which levels of HIV knowledge in the general population of sub‐Saharan Africa have changed in the current era of antiretroviral therapy (ART) scale‐up remains unknown. Methods Data on HIV knowledge in the general population were drawn from the 2003 to 2015 Demographic and Health Surveys (DHS) and AIDS Indicator Surveys (AIS) of 33 countries in sub‐Saharan Africa. The DHS/AIS contain five questions on HIV prevention and transmission that have been used by the Joint United Nations Programme on HIV/AIDS (UNAIDS) as a core indicator of HIV knowledge. We created a composite HIV knowledge variable equal to the number of correct responses to these five questions; a participant was considered to have comprehensive knowledge of HIV (yes/no) if he/she answered all five questions correctly. We fitted negative binomial regression models with cluster‐correlated robust standard errors and country fixed effects, adjusted for socio‐demographic variables, specifying HIV knowledge as the dependent variable and year as the explanatory variable. As an alternative parameterization, we also fitted a multivariable linear probability model with cluster‐correlated robust standard errors and country fixed effects specifying comprehensive knowledge of HIV as the dependent variable. Results A total of 791,186 women and 395,891 men participating in 75 DHS/AIS were included in the analyses. The mean HIV knowledge score was 3.7 among women and 3.9 among men (p