Radiographic Diagnosis of a Central Giant Cell Granuloma Using Advanced Imaging: Cone Beam Computed Tomography

Central giant cell granuloma (CGCG) is a benign non-neoplastic, proliferative intraosseous lesion of the jaw with an unknown etiology often diagnosed during the first two decades of life. The true nature of this lesion is controversial and remains elusive. Here, we report a case of central giant cel...

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Bibliographic Details
Published in:Curēus (Palo Alto, CA) CA), 2018-06, Vol.10 (6), p.e2735
Main Authors: Abdelkarim, Ahmed Z, Abu El Sadat, Shaimaa M, Chmieliauskaite, Milda, Syed, Ali Z
Format: Article
Language:English
Subjects:
Case reports
Dentistry
Drug dosages
Granulomas
Laboratories
Medical diagnosis
Medical imaging
Medicine
Otolaryngology
Pathology
Radiology
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Summary:Central giant cell granuloma (CGCG) is a benign non-neoplastic, proliferative intraosseous lesion of the jaw with an unknown etiology often diagnosed during the first two decades of life. The true nature of this lesion is controversial and remains elusive. Here, we report a case of central giant cell granuloma, diagnosed using cone-beam computed tomography (CBCT). A 21-year-old female presented to the clinic complaining of a painless swelling involving the right side of the mandible that had started one year previously. A CBCT scan revealed a well-defined, multilocular radiolucent lesion on the right side of the mandible extending from the molar region to the ramus with wispy septations. Wispy septations and undulating borders are some of the characteristic radiographic features of a central giant cell granuloma. The patient underwent an excisional biopsy. The biopsy revealed multinucleated giant cells in a fibrous stroma confirming our radiographic diagnosis of a central giant cell lesion.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.2735