Engineering precision biomaterials for personalized medicine

As the demand for precision medicine continues to rise, the "one-size-fits-all" approach to designing medical devices and therapies is becoming increasingly outdated. Biomaterials have considerable potential for transforming precision medicine, but individual patient complexity often neces...

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Bibliographic Details
Published in:Science translational medicine 2018-01, Vol.10 (424)
Main Authors: Aguado, Brian A, Grim, Joseph C, Rosales, Adrianne M, Watson-Capps, Jana J, Anseth, Kristi S
Format: Article
Language:English
Subjects:
Biocompatible Materials
Humans
Precision Medicine - methods
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Summary:As the demand for precision medicine continues to rise, the "one-size-fits-all" approach to designing medical devices and therapies is becoming increasingly outdated. Biomaterials have considerable potential for transforming precision medicine, but individual patient complexity often necessitates integrating multiple functions into a single device to successfully tailor personalized therapies. Here, we introduce an engineering strategy based on unit operations to provide a unified vocabulary and contextual framework to aid the design of biomaterial-based devices and accelerate their translation.
ISSN:1946-6234
1946-6242
DOI:10.1126/scitranslmed.aam8645