How accurate is the clinical and radiological evaluation of orbital lesions in comparison to surgical orbital biopsy?

Aims The purpose of the present study is to determine the overall and disease-related accuracy of clinical and radiological diagnosis when compared to the histology result of the surgical orbital biopsy. Methods A retrospective case notes analysis of patients who underwent surgical orbital biopsy du...

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Bibliographic Details
Published in:Eye (London) 2018-08, Vol.32 (8), p.1329-1333
Main Authors: Koukkoulli, A., Pilling, J. D., Patatas, K., El-Hindy, N., Chang, B., Kalantzis, G.
Format: Article
Language:English
Subjects:
692/698/1688/512/2613
692/699/3161
Adolescent
Adult
Aged
Aged, 80 and over
Biopsy
Biopsy - methods
Child
Child, Preschool
Diagnosis
Diagnosis, Differential
Female
Humans
Infant
Infant, Newborn
Inflammation
Laboratory Medicine
Magnetic Resonance Imaging - methods
Male
Medical diagnosis
Medicine
Medicine & Public Health
Middle Aged
Ophthalmologic Surgical Procedures - methods
Ophthalmology
Orbit - diagnostic imaging
Orbit - surgery
Orbital Diseases - diagnosis
Orbital Diseases - surgery
Pharmaceutical Sciences/Technology
Reproducibility of Results
Retrospective Studies
Surgery
Surgical Oncology
Tomography, X-Ray Computed - methods
Young Adult
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Summary:Aims The purpose of the present study is to determine the overall and disease-related accuracy of clinical and radiological diagnosis when compared to the histology result of the surgical orbital biopsy. Methods A retrospective case notes analysis of patients who underwent surgical orbital biopsy during a 12-year period involving more than 100 orbital lesions. The accuracy of clinical and radiological diagnosis was compared with histological diagnosis. Results A total of 112 orbital biopsies were carried out in 104 eyes of 101 patients between 2003 and 2015. Correct diagnosis was reached in
ISSN:0950-222X
1476-5454
DOI:10.1038/s41433-018-0078-3