Cardiac tamponade in a patient with ankylosing spondylitis: a notable response to TNF inhibitors

Ankylosing spondylitis (AS) is a rheumatological disorder of the spine, and like many other rheumatological diseases, it can manifest as a systemic inflammation. We present a rare case of cardiac manifestations of AS in a 25-year-old man with recurrent chest pain and pericardial effusions. He initia...

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Bibliographic Details
Published in:BMJ case reports 2018-08, Vol.2018, p.bcr-2017-224093
Main Authors: Kwan, Clara, Martirossian, Linett, Scheers-Masters, Joshua, Hollander, Gerald
Format: Article
Language:English
Subjects:
Acute coronary syndromes
Adalimumab - administration & dosage
Adalimumab - therapeutic use
Adult
Back pain
Cardiac Tamponade - complications
Cardiac Tamponade - diagnosis
Cardiac Tamponade - diagnostic imaging
Cardiac Tamponade - therapy
Cardiology
Case reports
Catheters
Chest Pain - etiology
Cocaine
Diagnosis, Differential
Echocardiography
Enzymes
Humans
Immunoglobulins
Male
Neutrophils
Nonsteroidal anti-inflammatory drugs
Pericardial Effusion - complications
Pericardial Effusion - diagnosis
Pericardial Effusion - diagnostic imaging
Pericardial Effusion - therapy
Pericardiocentesis
Rheumatology
Spondylitis, Ankylosing - complications
Spondylitis, Ankylosing - diagnosis
Spondylitis, Ankylosing - diagnostic imaging
Spondylitis, Ankylosing - drug therapy
Systemic diseases
Thoracic surgery
TNF inhibitors
Tumor Necrosis Factor-alpha - antagonists & inhibitors
Tumor necrosis factor-TNF
Ultrasonic imaging
Unusual Association of Diseases/Symptoms
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Description
Summary:Ankylosing spondylitis (AS) is a rheumatological disorder of the spine, and like many other rheumatological diseases, it can manifest as a systemic inflammation. We present a rare case of cardiac manifestations of AS in a 25-year-old man with recurrent chest pain and pericardial effusions. He initially presented with pleuritic chest pain, was diagnosed with cardiac tamponade and required emergent pericardiocentesis. The patient returned again with chest pain and was found to have reaccumulation of pericardial effusion. The cardiac symptoms were finally resolved when he was diagnosed and treated for AS.
ISSN:1757-790X
1757-790X
DOI:10.1136/bcr-2017-224093