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Analysis of melanoma recurrence following a negative sentinel lymph node biopsy
Little attention has been paid to the characteristics and outcomes of patients who experience distant, local or regional recurrence of melanoma following a negative sentinel lymph node biopsy. This article aims to review the published literature on the topic and presents some general summaries regar...
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Published in: | Melanoma management 2015-08, Vol.2 (3), p.285-294 |
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container_title | Melanoma management |
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creator | Hodges, Maggie Jones, Edward Jones, Teresa Pearlman, Nathan Gajdos, Csaba Kounalakis, Nicole McCarter, Martin |
description | Little attention has been paid to the characteristics and outcomes of patients who experience distant, local or regional recurrence of melanoma following a negative sentinel lymph node biopsy. This article aims to review the published literature on the topic and presents some general summaries regarding this patient population. Patients who experience a disease recurrence following a negative sentinel lymph node biopsy have a worse overall survival compared with patients with a positive sentinel lymph node biopsy. The implications and possible explanations for these findings are discussed in order to both underscore the need for in-depth investigation of local, regional or distant melanoma recurrence among patients following a true negative sentinel lymph node biopsy, as well as increased efforts to minimize the rate of false negative sentinel lymph node biopsies. |
doi_str_mv | 10.2217/mmt.15.19 |
format | article |
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subjects | false-negative rate melanoma outcomes recurrence sentinel lymph node survival Systematic Review |
title | Analysis of melanoma recurrence following a negative sentinel lymph node biopsy |
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