Candida auris, what do paediatricians need to know?

The newly recognised and emerging fungal species, Candida auris, has caused worldwide invasive infections and has been implicated in difficult to control hospital outbreaks. Challenges are encountered in the correct identification of this fungus as commonly used phenotypic and biochemical methods fa...

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Bibliographic Details
Published in:Archives of disease in childhood 2018-09, Vol.103 (9), p.891-894
Main Author: Warris, Adilia
Format: Article
Language:English
Subjects:
Abdomen
Abdominal surgery
Adults
Antifungal agents
Antifungal Agents - pharmacology
Antifungal Agents - therapeutic use
Candida
Candida - drug effects
Candida - isolation & purification
Candida auris
Candidiasis - drug therapy
Candidiasis - epidemiology
Candidiasis - microbiology
Drug Resistance, Fungal
Ear diseases
Epidemiology
Fluconazole
Fungal infections
Fungi
Humans
Infections
Microbial Sensitivity Tests
Mortality
Neonates
Newborn babies
Outbreaks
Outcomes of Treatment
Patients
Pediatrics
Pneumonia
Public health
Review
Sepsis
Species
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Summary:The newly recognised and emerging fungal species, Candida auris, has caused worldwide invasive infections and has been implicated in difficult to control hospital outbreaks. Challenges are encountered in the correct identification of this fungus as commonly used phenotypic and biochemical methods fail to differentiate C. auris from other Candida species. Its resistance profile, over 90% of isolates are fluconazole resistant and 35% are resistant to amphotericin, confronts clinicians with the restricted arsenal of antifungals and concerns about optimal treatment. The very first C. auris isolate was recovered from a paediatric patient in retrospect. Although infections with the more antifungal-resistant Candida species are less frequently observed in paediatric patients, this seems to be different for C. auris infections.
ISSN:0003-9888
1468-2044
1468-2044
DOI:10.1136/archdischild-2017-313960