Gestational Psittacosis Resulting in Neonatal Death Identified by Next-Generation RNA Sequencing of Postmortem, Formalin-Fixed Lung Tissue

Psittacosis is a rare zoonosis that can cause severe disease and adverse outcomes during pregnancy. We identified a previously elusive case of psittacosis causing premature delivery and infant death by next-generation RNA sequencing of postmortem tissues. Hypothesis-free pathogen detection in postmo...

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Bibliographic Details
Published in:Open forum infectious diseases 2018-08, Vol.5 (8), p.ofy172-ofy172
Main Authors: Paul, Litty, Comstock, Jessica, Edes, Kornelia, Schlaberg, Robert
Format: Article
Language:English
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Brief Report
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Summary:Psittacosis is a rare zoonosis that can cause severe disease and adverse outcomes during pregnancy. We identified a previously elusive case of psittacosis causing premature delivery and infant death by next-generation RNA sequencing of postmortem tissues. Hypothesis-free pathogen detection in postmortem specimens can increase the yield of epidemiologic and cause-of-death studies.
ISSN:2328-8957
2328-8957
DOI:10.1093/ofid/ofy172