Glioblastoma Multiforme Involving Conus Medullaris in a Child

Primary spinal cord glioblastoma multiforme involving the conus medullaris is an uncommon entity with poor outcomes. An aggressive multimodality treatment approach has been used, but prognosis remains same. There are no guidelines for the treatment of patients with spinal glioblastoma multiforme (GB...

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Bibliographic Details
Published in:Curēus (Palo Alto, CA) CA), 2018-06, Vol.10 (6), p.e2863
Main Authors: Mansha, Muhammad Atif, Khan, Agha Muhammad Hammad, Abbasi, Ahmed Nadeem N, Tariq, Muhammad Usman U, Mushtaq, Naureen, Tariq, Maria, Waheed, Asmara
Format: Article
Language:English
Subjects:
Back pain
Bone cancer
Brain cancer
Case reports
Cellular biology
Chemotherapy
Edema
Gangrene
Medical prognosis
Neurosurgery
NMR
Nuclear magnetic resonance
Patients
Pediatrics
Radiation Oncology
Radiation therapy
Spinal cancer
Spinal cord
Surgery
Surgical outcomes
Tumors
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Description
Summary:Primary spinal cord glioblastoma multiforme involving the conus medullaris is an uncommon entity with poor outcomes. An aggressive multimodality treatment approach has been used, but prognosis remains same. There are no guidelines for the treatment of patients with spinal glioblastoma multiforme (GBM). We highlight the case of a child diagnosed with conal GBM. He was treated with definitive surgery followed by adjuvant concurrent chemoradiation. After completion of treatment, he showed a temporary symptomatic improvement, but later on his condition deteriorated. We elaborate the stepwise treatment approach employed in this patient.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.2863