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Mediator: A Drawbridge across the Enhancer-Promoter Divide
Two papers in this issue of Molecular Cell provide insights into how the multisubunit Mediator coactivator complex dynamically links enhancer-bound activators to the RNA polymerase II machinery at the core promoter. Two papers in this issue of Molecular Cell provide insights into how the multisubuni...
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Published in: | Molecular cell 2016-11, Vol.64 (3), p.433-434 |
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description | Two papers in this issue of Molecular Cell provide insights into how the multisubunit Mediator coactivator complex dynamically links enhancer-bound activators to the RNA polymerase II machinery at the core promoter.
Two papers in this issue of Molecular Cell provide insights into how the multisubunit Mediator coactivator complex dynamically links enhancer-bound activators to the RNA polymerase II machinery at the core promoter. |
doi_str_mv | 10.1016/j.molcel.2016.10.024 |
format | article |
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subjects | Binding Sites Enhancer Elements, Genetic Gene Expression Regulation, Fungal Mediator Complex - genetics Mediator Complex - metabolism Promoter Regions, Genetic Protein Binding Protein Subunits - genetics Protein Subunits - metabolism RNA Polymerase II - genetics RNA Polymerase II - metabolism Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae - metabolism Saccharomyces cerevisiae Proteins - genetics Saccharomyces cerevisiae Proteins - metabolism Transcription Factor TFIIH - genetics Transcription Factor TFIIH - metabolism Transcription Initiation, Genetic Transcriptional Activation |
title | Mediator: A Drawbridge across the Enhancer-Promoter Divide |
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