Symmetric polyarthritis as an initial symptom in granulomatosis with polyangiitis: A report of six cases and review of the literature

Granulomatosis with polyangiitis (GPA) is a primary systemic vasculitis characterized by granulomatous inflammation. Arthritis in GPA is most commonly associated with large joints, particularly the knees and ankles; however, symmetrical polyarthritis of small joints has been rarely reported in liter...

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Bibliographic Details
Published in:European journal of rheumatology 2018-09, Vol.5 (3), p.191-193
Main Authors: Kısacık, Bünyamin, Önder, Mustafa Erkut, Sayarlıoğlu, Mehmet, Onat, Ahmet Mesut
Format: Article
Language:English
Subjects:
Arthritis
Case studies
Literature Review
Vasculitis
Wegener's granulomatosis
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Summary:Granulomatosis with polyangiitis (GPA) is a primary systemic vasculitis characterized by granulomatous inflammation. Arthritis in GPA is most commonly associated with large joints, particularly the knees and ankles; however, symmetrical polyarthritis of small joints has been rarely reported in literature. Here, we describe retrospective analysis of six patients with GPA showing initial symptom of symmetrical polyarthritis who were followed-up by three different rheumatology departments. Male sex, anti-cyclic citrulinated peptide negativity, and early arthritis period are important clues for GPA.
ISSN:2147-9720
2148-4279
DOI:10.5152/eurjrheum.2018.17050