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The Assessment of Serum Endocan Levels in Children With Juvenile Idiopathic Arthritis
This study aims to evaluate the levels of serum endocan in children with juvenile idiopathic arthritis (JIA). Sixty-seven children with JIA (30 males, 37 females; mean age 10.4±4.9 years; range 2 to 18 years) and a sex- and age- matched healthy control group of 39 children (16 males, 23 females; mea...
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Published in: | Archives of rheumatology 2018-06, Vol.33 (2), p.168-173 |
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container_title | Archives of rheumatology |
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creator | Yilmaz, Yasin Berru Durmuş, Rana Saraçoğlu, Başak Şahin, Sezgin Adrovic, Amra Barut, Kenan Özel Yildiz, Sevda Kasapçopur, Özgür Eker Ömeroğlu, Rukiye |
description | This study aims to evaluate the levels of serum endocan in children with juvenile idiopathic arthritis (JIA).
Sixty-seven children with JIA (30 males, 37 females; mean age 10.4±4.9 years; range 2 to 18 years) and a sex- and age- matched healthy control group of 39 children (16 males, 23 females; mean age 9.3±4.1 years; range 1 to 17 years) were recruited. Patients with JIA were divided into two groups as the clinically active JIA group (n=27) and inactive JIA group (n=40).
The median serum endocan level in patients with JIA was significantly higher than in the control group (633.75 ng/L vs. 379.76 ng/L, p |
doi_str_mv | 10.5606/ArchRheumatol.2018.6528 |
format | article |
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Sixty-seven children with JIA (30 males, 37 females; mean age 10.4±4.9 years; range 2 to 18 years) and a sex- and age- matched healthy control group of 39 children (16 males, 23 females; mean age 9.3±4.1 years; range 1 to 17 years) were recruited. Patients with JIA were divided into two groups as the clinically active JIA group (n=27) and inactive JIA group (n=40).
The median serum endocan level in patients with JIA was significantly higher than in the control group (633.75 ng/L vs. 379.76 ng/L, p<0.01). Comparison between patients with active JIA and inactive JIA was not significant in terms of endocan levels (618.70 ng/L vs. 687.36 ng/L, p=0.34). There was a weak negative correlation between Childhood Health Assessment Questionnaire scores of patients with JIA and serum endocan levels.
The high level of serum endocan highlighted the endothelial damage in patients with JIA.</description><identifier>ISSN: 2148-5046</identifier><identifier>EISSN: 2618-6500</identifier><identifier>DOI: 10.5606/ArchRheumatol.2018.6528</identifier><identifier>PMID: 30207559</identifier><language>eng</language><publisher>Turkey: Turkish League Against Rheumatism</publisher><subject>Analysis ; Arthritis ; Endothelium</subject><ispartof>Archives of rheumatology, 2018-06, Vol.33 (2), p.168-173</ispartof><rights>COPYRIGHT 2018 Turkish League Against Rheumatism</rights><rights>Copyright © 2018, Turkish League Against Rheumatism 2018 Turkish League Against Rheumatism</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c543t-78a38e3ec784c9b1d42d485133ad50e70f6e48a4a2f713c2ff097f775631cd293</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117134/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117134/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30207559$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Yilmaz, Yasin</creatorcontrib><creatorcontrib>Berru Durmuş, Rana</creatorcontrib><creatorcontrib>Saraçoğlu, Başak</creatorcontrib><creatorcontrib>Şahin, Sezgin</creatorcontrib><creatorcontrib>Adrovic, Amra</creatorcontrib><creatorcontrib>Barut, Kenan</creatorcontrib><creatorcontrib>Özel Yildiz, Sevda</creatorcontrib><creatorcontrib>Kasapçopur, Özgür</creatorcontrib><creatorcontrib>Eker Ömeroğlu, Rukiye</creatorcontrib><title>The Assessment of Serum Endocan Levels in Children With Juvenile Idiopathic Arthritis</title><title>Archives of rheumatology</title><addtitle>Arch Rheumatol</addtitle><description>This study aims to evaluate the levels of serum endocan in children with juvenile idiopathic arthritis (JIA).
Sixty-seven children with JIA (30 males, 37 females; mean age 10.4±4.9 years; range 2 to 18 years) and a sex- and age- matched healthy control group of 39 children (16 males, 23 females; mean age 9.3±4.1 years; range 1 to 17 years) were recruited. Patients with JIA were divided into two groups as the clinically active JIA group (n=27) and inactive JIA group (n=40).
The median serum endocan level in patients with JIA was significantly higher than in the control group (633.75 ng/L vs. 379.76 ng/L, p<0.01). Comparison between patients with active JIA and inactive JIA was not significant in terms of endocan levels (618.70 ng/L vs. 687.36 ng/L, p=0.34). There was a weak negative correlation between Childhood Health Assessment Questionnaire scores of patients with JIA and serum endocan levels.
The high level of serum endocan highlighted the endothelial damage in patients with JIA.</description><subject>Analysis</subject><subject>Arthritis</subject><subject>Endothelium</subject><issn>2148-5046</issn><issn>2618-6500</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><recordid>eNptkV9rFDEUxQdRbKn9ChoQfJs1mfydF2FYqq0sCNriY0gzN01kJlmS2YV-e7OsLV2Q-5AL-Z3Dvfc0zQeCV1xg8XnI1v_0sJvNkqZVh4laCd6pV815J4hqBcf4de0JUy3HTJw1l6X8wRgTJoXA9G1zRnGHJef9eXN36wENpUApM8QFJYd-Qd7N6CqOyZqINrCHqaAQ0dqHacwQ0e-wePR9t4cYJkA3Y0hbs_hg0ZAXn8MSyrvmjTNTgct_70Vz9_Xqdn3dbn58u1kPm9ZyRpdWKkMVULBSMdvfk5F1I1OcUGpGjkFiJ4Apw0znJKG2cw730knJBSV27Hp60Xw5-m539zOMtm6QzaS3OcwmP-pkgj79icHrh7TXgpDqyKrBx6PBg5lAh-hSxewcitUD7xUTrB6qUqv_ULVGmINNEVw9xKng0wuBBzMtvqRpt4QUyykoj6DNqZQM7nl2gvUhbH0Stj6ErQ9hV-X7l6s_656ipX8BcUOoeg</recordid><startdate>20180601</startdate><enddate>20180601</enddate><creator>Yilmaz, Yasin</creator><creator>Berru Durmuş, Rana</creator><creator>Saraçoğlu, Başak</creator><creator>Şahin, Sezgin</creator><creator>Adrovic, Amra</creator><creator>Barut, Kenan</creator><creator>Özel Yildiz, Sevda</creator><creator>Kasapçopur, Özgür</creator><creator>Eker Ömeroğlu, Rukiye</creator><general>Turkish League Against Rheumatism</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>5PM</scope></search><sort><creationdate>20180601</creationdate><title>The Assessment of Serum Endocan Levels in Children With Juvenile Idiopathic Arthritis</title><author>Yilmaz, Yasin ; Berru Durmuş, Rana ; Saraçoğlu, Başak ; Şahin, Sezgin ; Adrovic, Amra ; Barut, Kenan ; Özel Yildiz, Sevda ; Kasapçopur, Özgür ; Eker Ömeroğlu, Rukiye</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c543t-78a38e3ec784c9b1d42d485133ad50e70f6e48a4a2f713c2ff097f775631cd293</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Analysis</topic><topic>Arthritis</topic><topic>Endothelium</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Yilmaz, Yasin</creatorcontrib><creatorcontrib>Berru Durmuş, Rana</creatorcontrib><creatorcontrib>Saraçoğlu, Başak</creatorcontrib><creatorcontrib>Şahin, Sezgin</creatorcontrib><creatorcontrib>Adrovic, Amra</creatorcontrib><creatorcontrib>Barut, Kenan</creatorcontrib><creatorcontrib>Özel Yildiz, Sevda</creatorcontrib><creatorcontrib>Kasapçopur, Özgür</creatorcontrib><creatorcontrib>Eker Ömeroğlu, Rukiye</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Archives of rheumatology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yilmaz, Yasin</au><au>Berru Durmuş, Rana</au><au>Saraçoğlu, Başak</au><au>Şahin, Sezgin</au><au>Adrovic, Amra</au><au>Barut, Kenan</au><au>Özel Yildiz, Sevda</au><au>Kasapçopur, Özgür</au><au>Eker Ömeroğlu, Rukiye</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Assessment of Serum Endocan Levels in Children With Juvenile Idiopathic Arthritis</atitle><jtitle>Archives of rheumatology</jtitle><addtitle>Arch Rheumatol</addtitle><date>2018-06-01</date><risdate>2018</risdate><volume>33</volume><issue>2</issue><spage>168</spage><epage>173</epage><pages>168-173</pages><issn>2148-5046</issn><eissn>2618-6500</eissn><abstract>This study aims to evaluate the levels of serum endocan in children with juvenile idiopathic arthritis (JIA).
Sixty-seven children with JIA (30 males, 37 females; mean age 10.4±4.9 years; range 2 to 18 years) and a sex- and age- matched healthy control group of 39 children (16 males, 23 females; mean age 9.3±4.1 years; range 1 to 17 years) were recruited. Patients with JIA were divided into two groups as the clinically active JIA group (n=27) and inactive JIA group (n=40).
The median serum endocan level in patients with JIA was significantly higher than in the control group (633.75 ng/L vs. 379.76 ng/L, p<0.01). Comparison between patients with active JIA and inactive JIA was not significant in terms of endocan levels (618.70 ng/L vs. 687.36 ng/L, p=0.34). There was a weak negative correlation between Childhood Health Assessment Questionnaire scores of patients with JIA and serum endocan levels.
The high level of serum endocan highlighted the endothelial damage in patients with JIA.</abstract><cop>Turkey</cop><pub>Turkish League Against Rheumatism</pub><pmid>30207559</pmid><doi>10.5606/ArchRheumatol.2018.6528</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Analysis Arthritis Endothelium |
title | The Assessment of Serum Endocan Levels in Children With Juvenile Idiopathic Arthritis |
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