Recurrent chikungunya retinitis

Chikungunya is a systemic viral disease transmitted to humans by infected mosquitoes in endemic areas of Africa, Asia and more recently in the Americas. Chikungunya infection produces a sudden onset of fever, joint pains and erythematous skin eruption. A plethora of ocular manifestations have been d...

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Bibliographic Details
Published in:BMJ case reports 2018-08, Vol.2018, p.bcr-2017-222864
Main Authors: Salceanu, Silvia Olivia, Raman, Vasant
Format: Article
Language:English
Subjects:
Adrenal Cortex Hormones - therapeutic use
Adult
Authorship
Blood tests
Case reports
Chikungunya Fever - diagnosis
Chikungunya Fever - drug therapy
Chikungunya Fever - physiopathology
Chikungunya virus
Chikungunya virus - isolation & purification
Female
Fever
Humans
Infections
Lyme disease
Medical imaging
Mexico
Optics
Pathogenesis
Patients
Rare Disease
Recurrence
Retina
Retinitis - drug therapy
Retinitis - physiopathology
Retinitis - virology
RNA, Viral - blood
Steroids
Time Factors
Tomography
Travel
Treatment Outcome
United Kingdom
Viral infections
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Description
Summary:Chikungunya is a systemic viral disease transmitted to humans by infected mosquitoes in endemic areas of Africa, Asia and more recently in the Americas. Chikungunya infection produces a sudden onset of fever, joint pains and erythematous skin eruption. A plethora of ocular manifestations have been described ranging from a non-specific conjunctivitis to exudative retinal detachment. Ocular chikungunya seems to respond well to corticosteroid therapy, and outcomes are usually better if treated early. Our patient acquired this infection on a travel to Mexico jungle. This was confirmed by ReverseTranscriptase-PCR test once she returned to the UK. The peculiarity of the case is the inordinate delay of almost a year in the onset of eye symptoms, from acquiring the viral infection. The ocular inflammation responded to systemic corticosteroid therapy with a favourable visual outcome. She developed a recurrence many months later which again responded well to a course of oral steroids.
ISSN:1757-790X
1757-790X
DOI:10.1136/bcr-2017-222864