Innovative Approach of Non-Thermal Plasma Application for Improving the Growth Rate in Chickens

As an innovative technology in biological applications-non-thermal plasma technique-has recently been applied to living cells and tissues. However, it is unclear whether non-thermal plasma treatment can directly regulate the growth and development of livestock. In this study, we exposed four-day-inc...

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Bibliographic Details
Published in:International journal of molecular sciences 2018-08, Vol.19 (8), p.2301
Main Authors: Zhang, Jiao Jiao, Wang, Xian Zhong, Kwon, Taeho, Huynh, Do Luong, Chandimali, Nisansala, Kim, Nameun, Kang, Tae Yoon, Ghosh, Mrinmoy, Gera, Meeta, Lee, Sang Baek, Lee, Sung Jin, Lee, Wang Shik, Kim, Seong Bong, Mok, Young Sun, Jeong, Dong Kee
Format: Article
Language:English
Subjects:
Adenosine triphosphate
Adenosine Triphosphate - metabolism
Animals
Antioxidants
Biosynthesis
Chickens
Demethylation
Eggs
Gene expression
Glands
Growth factors
Growth Hormone - metabolism
Growth rate
Heat treatment
Homeostasis
Insulin
Insulin-Like Growth Factor I - metabolism
Livestock
Male
Metabolism
Mitochondria
Muscles
Plasma
Reactive oxygen species
Reactive Oxygen Species - metabolism
Skeletal muscle
Thermal plasmas
Thyroid gland
Thyroid hormones
Thyroid Hormones - metabolism
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Summary:As an innovative technology in biological applications-non-thermal plasma technique-has recently been applied to living cells and tissues. However, it is unclear whether non-thermal plasma treatment can directly regulate the growth and development of livestock. In this study, we exposed four-day-incubated fertilized eggs to plasma at 11.7 kV for 2 min, which was found to be the optimal condition in respect of highest growth rate in chickens. Interestingly, plasma-treated male chickens conspicuously grew faster than females. Plasma treatment regulated the reactive oxygen species homeostasis by controlling the mitochondrial respiratory complex activity and up-regulating the antioxidant defense system. At the same time, growth metabolism was improved due to the increase of growth hormone and insulin-like growth factor 1 and their receptors expression, and the rise of thyroid hormones and adenosine triphosphate levels through the regulation of demethylation levels of growth and hormone biosynthesis-related genes in the skeletal muscles and thyroid glands. To our knowledge, this study was the first to evaluate the effects of a non-thermal plasma treatment on the growth rate of chickens. This safe strategy might be beneficial to the livestock industry.
ISSN:1422-0067
1661-6596
1422-0067
DOI:10.3390/ijms19082301