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Results of Magnetic Sphincter Augmentation for Gastroesophageal Reflux Disease

Background Magnetic sphincter augmentation (MSA) is a modern treatment option for gastroesophageal reflux disease (GERD); however, laparoscopic fundoplication remains the gold standard. The aim of the study was to evaluate outcomes of MSA patients at a reflux center. Methods A retrospective review w...

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Published in:World journal of surgery 2018-10, Vol.42 (10), p.3263-3269
Main Authors: Schwameis, Katrin, Nikolic, Milena, Morales Castellano, Deivis G., Steindl, Ariane, Macheck, Sarah, Kristo, Ivan, Zörner, Barbara, Schoppmann, Sebastian F.
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creator Schwameis, Katrin
Nikolic, Milena
Morales Castellano, Deivis G.
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Kristo, Ivan
Zörner, Barbara
Schoppmann, Sebastian F.
description Background Magnetic sphincter augmentation (MSA) is a modern treatment option for gastroesophageal reflux disease (GERD); however, laparoscopic fundoplication remains the gold standard. The aim of the study was to evaluate outcomes of MSA patients at a reflux center. Methods A retrospective review was performed of all patients that underwent MSA between March 2012 and November 2017. Out of 110 patients, 68 with a follow-up >3 months were included. Postoperative gastrointestinal symptoms, proton pump inhibitor (PPI) intake, GERD-Health-related Quality of Life (GERD-HRQL) and alimentary satisfaction (AS) were assessed. Postoperative esophageal functioning tests were performed in 50% of patients. Results Sixty-eight patients underwent MSA; hiatal repair was performed in 31 cases. The median OR time was 27 min, and no intraoperative complications occurred. The median follow-up was 13 months (IQR 4.2–45). Endoscopic dilatation was performed in 2 patients (3%) and device removal in another 2 cases. The postoperative GERD-HRQL score was significantly reduced (3 vs. 24; p  
doi_str_mv 10.1007/s00268-018-4608-8
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The aim of the study was to evaluate outcomes of MSA patients at a reflux center. Methods A retrospective review was performed of all patients that underwent MSA between March 2012 and November 2017. Out of 110 patients, 68 with a follow-up &gt;3 months were included. Postoperative gastrointestinal symptoms, proton pump inhibitor (PPI) intake, GERD-Health-related Quality of Life (GERD-HRQL) and alimentary satisfaction (AS) were assessed. Postoperative esophageal functioning tests were performed in 50% of patients. Results Sixty-eight patients underwent MSA; hiatal repair was performed in 31 cases. The median OR time was 27 min, and no intraoperative complications occurred. The median follow-up was 13 months (IQR 4.2–45). Endoscopic dilatation was performed in 2 patients (3%) and device removal in another 2 cases. The postoperative GERD-HRQL score was significantly reduced (3 vs. 24; p  &lt; 0.001) and the median AS was 8/10. Preoperative experienced heartburn, regurgitations and dysphagia were eliminated in 92, 96 and 100%. Postoperative new-onset difficulties swallowing with solids only were reported to occur occasionally by 16% and rarely by 21% of patients. Satisfaction with heartburn relief was 95%, and the overall outcome was rated excellent/good in 89%. PPI dependency was eliminated in 87%. The median total percentage pH &lt; 4 and number of reflux episodes were significantly reduced. Postoperative pH results were negative or slightly above the norm in 79% and 12%, respectively. Conclusion Sphincter augmentation results in significantly reduced reflux symptoms, increased GERD-specific Quality of Life and excellent alimentary satisfaction with low perioperative morbidity. This procedure should be considered an excellent alternative to fundoplication in the treatment of GERD.</description><identifier>ISSN: 0364-2313</identifier><identifier>EISSN: 1432-2323</identifier><identifier>DOI: 10.1007/s00268-018-4608-8</identifier><identifier>PMID: 29619511</identifier><language>eng</language><publisher>Cham: Springer International Publishing</publisher><subject>Abdominal Surgery ; Adult ; Augmentation ; Cardiac Surgery ; Complications ; Dysphagia ; Esophageal Sphincter, Lower - surgery ; Esophagus ; Female ; Gastroesophageal reflux ; Gastroesophageal Reflux - drug therapy ; Gastroesophageal Reflux - surgery ; Gastrointestinal symptoms ; General Surgery ; Hernias ; Humans ; Laparoscopy ; Male ; Medical treatment ; Medicine ; Medicine &amp; Public Health ; Middle Aged ; Morbidity ; Original Scientific Report ; Patients ; pH effects ; Prosthesis Implantation - instrumentation ; Prosthesis Implantation - methods ; Proton pump inhibitors ; Proton Pump Inhibitors - therapeutic use ; Quality of life ; Retrospective Studies ; Sphincter ; Surgery ; Swallowing ; Thoracic Surgery ; Treatment Outcome ; Vascular Surgery</subject><ispartof>World journal of surgery, 2018-10, Vol.42 (10), p.3263-3269</ispartof><rights>The Author(s) 2018</rights><rights>2018 The Author(s)</rights><rights>World Journal of Surgery is a copyright of Springer, (2018). All Rights Reserved. © 2018. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5207-f3fe6dbb39075446a72767becb1a0e06069a7754a0c133f5a36e0cce564d391a3</citedby><cites>FETCH-LOGICAL-c5207-f3fe6dbb39075446a72767becb1a0e06069a7754a0c133f5a36e0cce564d391a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,780,784,885,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29619511$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Schwameis, Katrin</creatorcontrib><creatorcontrib>Nikolic, Milena</creatorcontrib><creatorcontrib>Morales Castellano, Deivis G.</creatorcontrib><creatorcontrib>Steindl, Ariane</creatorcontrib><creatorcontrib>Macheck, Sarah</creatorcontrib><creatorcontrib>Kristo, Ivan</creatorcontrib><creatorcontrib>Zörner, Barbara</creatorcontrib><creatorcontrib>Schoppmann, Sebastian F.</creatorcontrib><title>Results of Magnetic Sphincter Augmentation for Gastroesophageal Reflux Disease</title><title>World journal of surgery</title><addtitle>World J Surg</addtitle><addtitle>World J Surg</addtitle><description>Background Magnetic sphincter augmentation (MSA) is a modern treatment option for gastroesophageal reflux disease (GERD); however, laparoscopic fundoplication remains the gold standard. The aim of the study was to evaluate outcomes of MSA patients at a reflux center. Methods A retrospective review was performed of all patients that underwent MSA between March 2012 and November 2017. Out of 110 patients, 68 with a follow-up &gt;3 months were included. Postoperative gastrointestinal symptoms, proton pump inhibitor (PPI) intake, GERD-Health-related Quality of Life (GERD-HRQL) and alimentary satisfaction (AS) were assessed. Postoperative esophageal functioning tests were performed in 50% of patients. Results Sixty-eight patients underwent MSA; hiatal repair was performed in 31 cases. The median OR time was 27 min, and no intraoperative complications occurred. The median follow-up was 13 months (IQR 4.2–45). Endoscopic dilatation was performed in 2 patients (3%) and device removal in another 2 cases. The postoperative GERD-HRQL score was significantly reduced (3 vs. 24; p  &lt; 0.001) and the median AS was 8/10. Preoperative experienced heartburn, regurgitations and dysphagia were eliminated in 92, 96 and 100%. Postoperative new-onset difficulties swallowing with solids only were reported to occur occasionally by 16% and rarely by 21% of patients. Satisfaction with heartburn relief was 95%, and the overall outcome was rated excellent/good in 89%. PPI dependency was eliminated in 87%. The median total percentage pH &lt; 4 and number of reflux episodes were significantly reduced. Postoperative pH results were negative or slightly above the norm in 79% and 12%, respectively. Conclusion Sphincter augmentation results in significantly reduced reflux symptoms, increased GERD-specific Quality of Life and excellent alimentary satisfaction with low perioperative morbidity. 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however, laparoscopic fundoplication remains the gold standard. The aim of the study was to evaluate outcomes of MSA patients at a reflux center. Methods A retrospective review was performed of all patients that underwent MSA between March 2012 and November 2017. Out of 110 patients, 68 with a follow-up &gt;3 months were included. Postoperative gastrointestinal symptoms, proton pump inhibitor (PPI) intake, GERD-Health-related Quality of Life (GERD-HRQL) and alimentary satisfaction (AS) were assessed. Postoperative esophageal functioning tests were performed in 50% of patients. Results Sixty-eight patients underwent MSA; hiatal repair was performed in 31 cases. The median OR time was 27 min, and no intraoperative complications occurred. The median follow-up was 13 months (IQR 4.2–45). Endoscopic dilatation was performed in 2 patients (3%) and device removal in another 2 cases. The postoperative GERD-HRQL score was significantly reduced (3 vs. 24; p  &lt; 0.001) and the median AS was 8/10. Preoperative experienced heartburn, regurgitations and dysphagia were eliminated in 92, 96 and 100%. Postoperative new-onset difficulties swallowing with solids only were reported to occur occasionally by 16% and rarely by 21% of patients. Satisfaction with heartburn relief was 95%, and the overall outcome was rated excellent/good in 89%. PPI dependency was eliminated in 87%. The median total percentage pH &lt; 4 and number of reflux episodes were significantly reduced. Postoperative pH results were negative or slightly above the norm in 79% and 12%, respectively. Conclusion Sphincter augmentation results in significantly reduced reflux symptoms, increased GERD-specific Quality of Life and excellent alimentary satisfaction with low perioperative morbidity. This procedure should be considered an excellent alternative to fundoplication in the treatment of GERD.</abstract><cop>Cham</cop><pub>Springer International Publishing</pub><pmid>29619511</pmid><doi>10.1007/s00268-018-4608-8</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record>
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subjects Abdominal Surgery
Adult
Augmentation
Cardiac Surgery
Complications
Dysphagia
Esophageal Sphincter, Lower - surgery
Esophagus
Female
Gastroesophageal reflux
Gastroesophageal Reflux - drug therapy
Gastroesophageal Reflux - surgery
Gastrointestinal symptoms
General Surgery
Hernias
Humans
Laparoscopy
Male
Medical treatment
Medicine
Medicine & Public Health
Middle Aged
Morbidity
Original Scientific Report
Patients
pH effects
Prosthesis Implantation - instrumentation
Prosthesis Implantation - methods
Proton pump inhibitors
Proton Pump Inhibitors - therapeutic use
Quality of life
Retrospective Studies
Sphincter
Surgery
Swallowing
Thoracic Surgery
Treatment Outcome
Vascular Surgery
title Results of Magnetic Sphincter Augmentation for Gastroesophageal Reflux Disease
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