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Results of Magnetic Sphincter Augmentation for Gastroesophageal Reflux Disease
Background Magnetic sphincter augmentation (MSA) is a modern treatment option for gastroesophageal reflux disease (GERD); however, laparoscopic fundoplication remains the gold standard. The aim of the study was to evaluate outcomes of MSA patients at a reflux center. Methods A retrospective review w...
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Published in: | World journal of surgery 2018-10, Vol.42 (10), p.3263-3269 |
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description | Background
Magnetic sphincter augmentation (MSA) is a modern treatment option for gastroesophageal reflux disease (GERD); however, laparoscopic fundoplication remains the gold standard. The aim of the study was to evaluate outcomes of MSA patients at a reflux center.
Methods
A retrospective review was performed of all patients that underwent MSA between March 2012 and November 2017. Out of 110 patients, 68 with a follow-up >3 months were included. Postoperative gastrointestinal symptoms, proton pump inhibitor (PPI) intake, GERD-Health-related Quality of Life (GERD-HRQL) and alimentary satisfaction (AS) were assessed. Postoperative esophageal functioning tests were performed in 50% of patients.
Results
Sixty-eight patients underwent MSA; hiatal repair was performed in 31 cases. The median OR time was 27 min, and no intraoperative complications occurred. The median follow-up was 13 months (IQR 4.2–45). Endoscopic dilatation was performed in 2 patients (3%) and device removal in another 2 cases. The postoperative GERD-HRQL score was significantly reduced (3 vs. 24;
p
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doi_str_mv | 10.1007/s00268-018-4608-8 |
format | article |
fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6132868</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2022130682</sourcerecordid><originalsourceid>FETCH-LOGICAL-c5207-f3fe6dbb39075446a72767becb1a0e06069a7754a0c133f5a36e0cce564d391a3</originalsourceid><addsrcrecordid>eNqFkc1v1DAQxa2qqF0KfwAXFKkXLoGxnfjjUqkUWkAFpJaqR8vxTrKusvFiJ0D_e7xKKR9SxWlGmt97eqNHyDMKLymAfJUAmFAlUFVWAlSpdsiCVpyVjDO-SxbARZV3yvfJ45RuAKgUIPbIPtOC6prSBfl0gWnqx1SEtvhouwFH74rLzcoPbsRYHE_dGofRjj4MRRticWbTGAOmsFnZDm1fXGDbTz-KNz6hTfiEPGptn_Dp3TwgV6dvv5y8K88_n70_OT4vXc1Ali1vUSybhmuQdVUJK5kUskHXUAsIOaS2Ml8sOMp5W1suEJzDWlRLrqnlB-Ro9t1MzRqXLmeMtjeb6Nc23ppgvfn7MviV6cI3IyhnSqhs8OLOIIavE6bRrH1y2Pd2wDAlw4AxykEoltHDf9CbMMUhv7elqKyVriBTdKZcDClFbO_DUDDbtszclsltmW1bZhvi-Z9f3Ct-1ZMBPQPffY-3_3c01x8uX5-C0lpmLZu1KcuGDuPv2A8n-gmlCbEW</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2021758940</pqid></control><display><type>article</type><title>Results of Magnetic Sphincter Augmentation for Gastroesophageal Reflux Disease</title><source>Springer Link</source><creator>Schwameis, Katrin ; Nikolic, Milena ; Morales Castellano, Deivis G. ; Steindl, Ariane ; Macheck, Sarah ; Kristo, Ivan ; Zörner, Barbara ; Schoppmann, Sebastian F.</creator><creatorcontrib>Schwameis, Katrin ; Nikolic, Milena ; Morales Castellano, Deivis G. ; Steindl, Ariane ; Macheck, Sarah ; Kristo, Ivan ; Zörner, Barbara ; Schoppmann, Sebastian F.</creatorcontrib><description>Background
Magnetic sphincter augmentation (MSA) is a modern treatment option for gastroesophageal reflux disease (GERD); however, laparoscopic fundoplication remains the gold standard. The aim of the study was to evaluate outcomes of MSA patients at a reflux center.
Methods
A retrospective review was performed of all patients that underwent MSA between March 2012 and November 2017. Out of 110 patients, 68 with a follow-up >3 months were included. Postoperative gastrointestinal symptoms, proton pump inhibitor (PPI) intake, GERD-Health-related Quality of Life (GERD-HRQL) and alimentary satisfaction (AS) were assessed. Postoperative esophageal functioning tests were performed in 50% of patients.
Results
Sixty-eight patients underwent MSA; hiatal repair was performed in 31 cases. The median OR time was 27 min, and no intraoperative complications occurred. The median follow-up was 13 months (IQR 4.2–45). Endoscopic dilatation was performed in 2 patients (3%) and device removal in another 2 cases. The postoperative GERD-HRQL score was significantly reduced (3 vs. 24;
p
< 0.001) and the median AS was 8/10. Preoperative experienced heartburn, regurgitations and dysphagia were eliminated in 92, 96 and 100%. Postoperative new-onset difficulties swallowing with solids only were reported to occur occasionally by 16% and rarely by 21% of patients. Satisfaction with heartburn relief was 95%, and the overall outcome was rated excellent/good in 89%. PPI dependency was eliminated in 87%. The median total percentage pH < 4 and number of reflux episodes were significantly reduced. Postoperative pH results were negative or slightly above the norm in 79% and 12%, respectively.
Conclusion
Sphincter augmentation results in significantly reduced reflux symptoms, increased GERD-specific Quality of Life and excellent alimentary satisfaction with low perioperative morbidity. This procedure should be considered an excellent alternative to fundoplication in the treatment of GERD.</description><identifier>ISSN: 0364-2313</identifier><identifier>EISSN: 1432-2323</identifier><identifier>DOI: 10.1007/s00268-018-4608-8</identifier><identifier>PMID: 29619511</identifier><language>eng</language><publisher>Cham: Springer International Publishing</publisher><subject>Abdominal Surgery ; Adult ; Augmentation ; Cardiac Surgery ; Complications ; Dysphagia ; Esophageal Sphincter, Lower - surgery ; Esophagus ; Female ; Gastroesophageal reflux ; Gastroesophageal Reflux - drug therapy ; Gastroesophageal Reflux - surgery ; Gastrointestinal symptoms ; General Surgery ; Hernias ; Humans ; Laparoscopy ; Male ; Medical treatment ; Medicine ; Medicine & Public Health ; Middle Aged ; Morbidity ; Original Scientific Report ; Patients ; pH effects ; Prosthesis Implantation - instrumentation ; Prosthesis Implantation - methods ; Proton pump inhibitors ; Proton Pump Inhibitors - therapeutic use ; Quality of life ; Retrospective Studies ; Sphincter ; Surgery ; Swallowing ; Thoracic Surgery ; Treatment Outcome ; Vascular Surgery</subject><ispartof>World journal of surgery, 2018-10, Vol.42 (10), p.3263-3269</ispartof><rights>The Author(s) 2018</rights><rights>2018 The Author(s)</rights><rights>World Journal of Surgery is a copyright of Springer, (2018). All Rights Reserved. © 2018. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5207-f3fe6dbb39075446a72767becb1a0e06069a7754a0c133f5a36e0cce564d391a3</citedby><cites>FETCH-LOGICAL-c5207-f3fe6dbb39075446a72767becb1a0e06069a7754a0c133f5a36e0cce564d391a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,780,784,885,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29619511$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Schwameis, Katrin</creatorcontrib><creatorcontrib>Nikolic, Milena</creatorcontrib><creatorcontrib>Morales Castellano, Deivis G.</creatorcontrib><creatorcontrib>Steindl, Ariane</creatorcontrib><creatorcontrib>Macheck, Sarah</creatorcontrib><creatorcontrib>Kristo, Ivan</creatorcontrib><creatorcontrib>Zörner, Barbara</creatorcontrib><creatorcontrib>Schoppmann, Sebastian F.</creatorcontrib><title>Results of Magnetic Sphincter Augmentation for Gastroesophageal Reflux Disease</title><title>World journal of surgery</title><addtitle>World J Surg</addtitle><addtitle>World J Surg</addtitle><description>Background
Magnetic sphincter augmentation (MSA) is a modern treatment option for gastroesophageal reflux disease (GERD); however, laparoscopic fundoplication remains the gold standard. The aim of the study was to evaluate outcomes of MSA patients at a reflux center.
Methods
A retrospective review was performed of all patients that underwent MSA between March 2012 and November 2017. Out of 110 patients, 68 with a follow-up >3 months were included. Postoperative gastrointestinal symptoms, proton pump inhibitor (PPI) intake, GERD-Health-related Quality of Life (GERD-HRQL) and alimentary satisfaction (AS) were assessed. Postoperative esophageal functioning tests were performed in 50% of patients.
Results
Sixty-eight patients underwent MSA; hiatal repair was performed in 31 cases. The median OR time was 27 min, and no intraoperative complications occurred. The median follow-up was 13 months (IQR 4.2–45). Endoscopic dilatation was performed in 2 patients (3%) and device removal in another 2 cases. The postoperative GERD-HRQL score was significantly reduced (3 vs. 24;
p
< 0.001) and the median AS was 8/10. Preoperative experienced heartburn, regurgitations and dysphagia were eliminated in 92, 96 and 100%. Postoperative new-onset difficulties swallowing with solids only were reported to occur occasionally by 16% and rarely by 21% of patients. Satisfaction with heartburn relief was 95%, and the overall outcome was rated excellent/good in 89%. PPI dependency was eliminated in 87%. The median total percentage pH < 4 and number of reflux episodes were significantly reduced. Postoperative pH results were negative or slightly above the norm in 79% and 12%, respectively.
Conclusion
Sphincter augmentation results in significantly reduced reflux symptoms, increased GERD-specific Quality of Life and excellent alimentary satisfaction with low perioperative morbidity. This procedure should be considered an excellent alternative to fundoplication in the treatment of GERD.</description><subject>Abdominal Surgery</subject><subject>Adult</subject><subject>Augmentation</subject><subject>Cardiac Surgery</subject><subject>Complications</subject><subject>Dysphagia</subject><subject>Esophageal Sphincter, Lower - surgery</subject><subject>Esophagus</subject><subject>Female</subject><subject>Gastroesophageal reflux</subject><subject>Gastroesophageal Reflux - drug therapy</subject><subject>Gastroesophageal Reflux - surgery</subject><subject>Gastrointestinal symptoms</subject><subject>General Surgery</subject><subject>Hernias</subject><subject>Humans</subject><subject>Laparoscopy</subject><subject>Male</subject><subject>Medical treatment</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Morbidity</subject><subject>Original Scientific Report</subject><subject>Patients</subject><subject>pH effects</subject><subject>Prosthesis Implantation - instrumentation</subject><subject>Prosthesis Implantation - methods</subject><subject>Proton pump inhibitors</subject><subject>Proton Pump Inhibitors - therapeutic use</subject><subject>Quality of life</subject><subject>Retrospective Studies</subject><subject>Sphincter</subject><subject>Surgery</subject><subject>Swallowing</subject><subject>Thoracic Surgery</subject><subject>Treatment Outcome</subject><subject>Vascular Surgery</subject><issn>0364-2313</issn><issn>1432-2323</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>24P</sourceid><recordid>eNqFkc1v1DAQxa2qqF0KfwAXFKkXLoGxnfjjUqkUWkAFpJaqR8vxTrKusvFiJ0D_e7xKKR9SxWlGmt97eqNHyDMKLymAfJUAmFAlUFVWAlSpdsiCVpyVjDO-SxbARZV3yvfJ45RuAKgUIPbIPtOC6prSBfl0gWnqx1SEtvhouwFH74rLzcoPbsRYHE_dGofRjj4MRRticWbTGAOmsFnZDm1fXGDbTz-KNz6hTfiEPGptn_Dp3TwgV6dvv5y8K88_n70_OT4vXc1Ali1vUSybhmuQdVUJK5kUskHXUAsIOaS2Ml8sOMp5W1suEJzDWlRLrqnlB-Ro9t1MzRqXLmeMtjeb6Nc23ppgvfn7MviV6cI3IyhnSqhs8OLOIIavE6bRrH1y2Pd2wDAlw4AxykEoltHDf9CbMMUhv7elqKyVriBTdKZcDClFbO_DUDDbtszclsltmW1bZhvi-Z9f3Ct-1ZMBPQPffY-3_3c01x8uX5-C0lpmLZu1KcuGDuPv2A8n-gmlCbEW</recordid><startdate>201810</startdate><enddate>201810</enddate><creator>Schwameis, Katrin</creator><creator>Nikolic, Milena</creator><creator>Morales Castellano, Deivis G.</creator><creator>Steindl, Ariane</creator><creator>Macheck, Sarah</creator><creator>Kristo, Ivan</creator><creator>Zörner, Barbara</creator><creator>Schoppmann, Sebastian F.</creator><general>Springer International Publishing</general><general>Springer Nature B.V</general><scope>C6C</scope><scope>24P</scope><scope>WIN</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QO</scope><scope>7T5</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>H94</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>201810</creationdate><title>Results of Magnetic Sphincter Augmentation for Gastroesophageal Reflux Disease</title><author>Schwameis, Katrin ; Nikolic, Milena ; Morales Castellano, Deivis G. ; Steindl, Ariane ; Macheck, Sarah ; Kristo, Ivan ; Zörner, Barbara ; Schoppmann, Sebastian F.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5207-f3fe6dbb39075446a72767becb1a0e06069a7754a0c133f5a36e0cce564d391a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Abdominal Surgery</topic><topic>Adult</topic><topic>Augmentation</topic><topic>Cardiac Surgery</topic><topic>Complications</topic><topic>Dysphagia</topic><topic>Esophageal Sphincter, Lower - surgery</topic><topic>Esophagus</topic><topic>Female</topic><topic>Gastroesophageal reflux</topic><topic>Gastroesophageal Reflux - drug therapy</topic><topic>Gastroesophageal Reflux - surgery</topic><topic>Gastrointestinal symptoms</topic><topic>General Surgery</topic><topic>Hernias</topic><topic>Humans</topic><topic>Laparoscopy</topic><topic>Male</topic><topic>Medical treatment</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Morbidity</topic><topic>Original Scientific Report</topic><topic>Patients</topic><topic>pH effects</topic><topic>Prosthesis Implantation - instrumentation</topic><topic>Prosthesis Implantation - methods</topic><topic>Proton pump inhibitors</topic><topic>Proton Pump Inhibitors - therapeutic use</topic><topic>Quality of life</topic><topic>Retrospective Studies</topic><topic>Sphincter</topic><topic>Surgery</topic><topic>Swallowing</topic><topic>Thoracic Surgery</topic><topic>Treatment Outcome</topic><topic>Vascular Surgery</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Schwameis, Katrin</creatorcontrib><creatorcontrib>Nikolic, Milena</creatorcontrib><creatorcontrib>Morales Castellano, Deivis G.</creatorcontrib><creatorcontrib>Steindl, Ariane</creatorcontrib><creatorcontrib>Macheck, Sarah</creatorcontrib><creatorcontrib>Kristo, Ivan</creatorcontrib><creatorcontrib>Zörner, Barbara</creatorcontrib><creatorcontrib>Schoppmann, Sebastian F.</creatorcontrib><collection>SpringerOpen</collection><collection>Open Access: Wiley-Blackwell Open Access Journals</collection><collection>Wiley-Blackwell Free Backfiles(OpenAccess)</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Biotechnology Research Abstracts</collection><collection>Immunology Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>World journal of surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Schwameis, Katrin</au><au>Nikolic, Milena</au><au>Morales Castellano, Deivis G.</au><au>Steindl, Ariane</au><au>Macheck, Sarah</au><au>Kristo, Ivan</au><au>Zörner, Barbara</au><au>Schoppmann, Sebastian F.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Results of Magnetic Sphincter Augmentation for Gastroesophageal Reflux Disease</atitle><jtitle>World journal of surgery</jtitle><stitle>World J Surg</stitle><addtitle>World J Surg</addtitle><date>2018-10</date><risdate>2018</risdate><volume>42</volume><issue>10</issue><spage>3263</spage><epage>3269</epage><pages>3263-3269</pages><issn>0364-2313</issn><eissn>1432-2323</eissn><abstract>Background
Magnetic sphincter augmentation (MSA) is a modern treatment option for gastroesophageal reflux disease (GERD); however, laparoscopic fundoplication remains the gold standard. The aim of the study was to evaluate outcomes of MSA patients at a reflux center.
Methods
A retrospective review was performed of all patients that underwent MSA between March 2012 and November 2017. Out of 110 patients, 68 with a follow-up >3 months were included. Postoperative gastrointestinal symptoms, proton pump inhibitor (PPI) intake, GERD-Health-related Quality of Life (GERD-HRQL) and alimentary satisfaction (AS) were assessed. Postoperative esophageal functioning tests were performed in 50% of patients.
Results
Sixty-eight patients underwent MSA; hiatal repair was performed in 31 cases. The median OR time was 27 min, and no intraoperative complications occurred. The median follow-up was 13 months (IQR 4.2–45). Endoscopic dilatation was performed in 2 patients (3%) and device removal in another 2 cases. The postoperative GERD-HRQL score was significantly reduced (3 vs. 24;
p
< 0.001) and the median AS was 8/10. Preoperative experienced heartburn, regurgitations and dysphagia were eliminated in 92, 96 and 100%. Postoperative new-onset difficulties swallowing with solids only were reported to occur occasionally by 16% and rarely by 21% of patients. Satisfaction with heartburn relief was 95%, and the overall outcome was rated excellent/good in 89%. PPI dependency was eliminated in 87%. The median total percentage pH < 4 and number of reflux episodes were significantly reduced. Postoperative pH results were negative or slightly above the norm in 79% and 12%, respectively.
Conclusion
Sphincter augmentation results in significantly reduced reflux symptoms, increased GERD-specific Quality of Life and excellent alimentary satisfaction with low perioperative morbidity. This procedure should be considered an excellent alternative to fundoplication in the treatment of GERD.</abstract><cop>Cham</cop><pub>Springer International Publishing</pub><pmid>29619511</pmid><doi>10.1007/s00268-018-4608-8</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Abdominal Surgery Adult Augmentation Cardiac Surgery Complications Dysphagia Esophageal Sphincter, Lower - surgery Esophagus Female Gastroesophageal reflux Gastroesophageal Reflux - drug therapy Gastroesophageal Reflux - surgery Gastrointestinal symptoms General Surgery Hernias Humans Laparoscopy Male Medical treatment Medicine Medicine & Public Health Middle Aged Morbidity Original Scientific Report Patients pH effects Prosthesis Implantation - instrumentation Prosthesis Implantation - methods Proton pump inhibitors Proton Pump Inhibitors - therapeutic use Quality of life Retrospective Studies Sphincter Surgery Swallowing Thoracic Surgery Treatment Outcome Vascular Surgery |
title | Results of Magnetic Sphincter Augmentation for Gastroesophageal Reflux Disease |
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