Clear cell sarcoma-A review

Abstract Clear cell sarcoma (CCS) previously known as malignant melanoma (MM) of the soft tissue, although, similar in morphology to MM, contemporary histopathologic and cytogenetic techniques have made this diagnosis obsolete, as it is now possible to distinguish between CCS and MM. CCS is often di...

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Bibliographic Details
Published in:Journal of orthopaedics 2018-12, Vol.15 (4), p.963-966
Main Authors: Ibrahim, Rami Mossad, Steenstrup Jensen, Signe, Juel, Jacob
Format: Article
Language:English
Subjects:
Clear cell sarcoma
Malignant melanoma of the soft tissue
Orthopedics
Sarcoma
Treatment of clear cell sarcoma
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Summary:Abstract Clear cell sarcoma (CCS) previously known as malignant melanoma (MM) of the soft tissue, although, similar in morphology to MM, contemporary histopathologic and cytogenetic techniques have made this diagnosis obsolete, as it is now possible to distinguish between CCS and MM. CCS is often diagnosed in young adults with median age of 25 years. Overall mortality is generally poor, and the 5-year survival is between 40 and 60%. Hence, early diagnosis and radical surgery are key in the treatment of this extremely rare malignancy of the soft tissue comprising only about 1% of all sarcomas. This article present an overview of this rare malignancy.
ISSN:0972-978X
0972-978X
DOI:10.1016/j.jor.2018.08.039