Consumption of Fish and Shrimp from Southeast Louisiana Poses No Unacceptable Lifetime Cancer Risks Attributable to High‐Priority Polycyclic Aromatic Hydrocarbons

• Published in: Risk analysis 2018-09, Vol.38 (9), p.1944-1961
• Main Authors: Wickliffe, Jeffrey K., Simon‐Friedt, Bridget, Howard, Jessi L., Frahm, Ericka, Meyer, Buffy, Wilson, Mark J., Pangeni, Deepa, Overton, Edward B.
• Format: Article
• Language: English
• Subjects: Accidents; Algorithms; Animals; Cancer; Carcinogens; Chemical spills; Chemicals; Consumers; Consumption; Consumption health risks; Contamination; Crude oil; Detection limits; Environmental Monitoring - methods; Female; Fish; Fish Products; Food Contamination - analysis; Gas Chromatography-Mass Spectrometry; Health risk assessment; Health risks; Humans; Hydrocarbons; Louisiana; Neoplasms - chemically induced; Neoplasms - epidemiology; Oil pollution; oil spill; Oil spills; Organic chemistry; Penaeidae; Petroleum; Petroleum - analysis; Petroleum Pollution; Polycyclic aromatic hydrocarbons; Polycyclic Aromatic Hydrocarbons - analysis; Probability; Quality Control; Risk Assessment; Risk factors; Seafood; Seafood - analysis; Water Pollutants, Chemical - analysis
• ISSN: 0272-4332; 1539-6924
• DOI: 10.1111/risa.12985

Following oil spills such as the Deepwater Horizon accident (DWH), contamination of seafood resources and possible increased health risks attributable to consumption of seafood in spill areas are major concerns. In this study, locally harvested finfish and shrimp were collected from research participants in southeast Louisiana and analyzed for polycyclic aromatic hydrocarbons (PAHs). PAHs are some of the most important chemicals of concern regarding oil‐spill‐contaminated seafood resources during and following oil spills. Some PAHs are considered carcinogens for risk assessment purposes, and currently, seven of these can be combined in lifetime cancer risk assessments using EPA approaches. Most PAHs were not detected in these samples (minimum detection limits ranged from 1.2 to 2.1 PPB) and of those that were detected, they were generally below 10 PPB. The pattern of detected PAHs suggested that the source of these chemicals in these seafood samples was not a result of direct contact with crude oil. Lifetime cancer risks were assessed using conservative assumptions and models in a probabilistic framework for the seven carcinogenic PAHs. Lifetime health risks modeled using this framework did not exceed a 1/10,000 cancer risk threshold. Conservative, health‐protective deterministic estimates of the levels of concern for PAH chemical concentration and seafood intake rates were above the concentrations and intake rates modeled under this probabilistic framework. Taken together, consumption of finfish and shrimp harvested from southeast Louisiana following the DWH does not pose unacceptable lifetime cancer risks from these seven carcinogenic PAHs even for the heaviest possible consumers.