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Miller Fisher Syndrome Associated With Immunotherapy for Metastatic Melanoma
Immunotherapy is a treatment strategy that has demonstrated survival benefit for metastatic melanoma. Ipilimumab and nivolumab are examples of immunotherapy, in which monoclonal antibodies antagonize cytotoxic T-lymphocyte-associated protein 4 and programmed death-ligand 1 receptors, respectively, r...
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Published in: | Neurohospitalist 2018-10, Vol.8 (4), p.191-193 |
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container_issue | 4 |
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container_title | Neurohospitalist |
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creator | Baird-Gunning, Jonathan J. D. Weerasinghe, Dinushi Silsby, Matthew Gawarikar, Yash Carlino, Matteo S. Smith, Jessica L. Vucic, Steve |
description | Immunotherapy is a treatment strategy that has demonstrated survival benefit for metastatic melanoma. Ipilimumab and nivolumab are examples of immunotherapy, in which monoclonal antibodies antagonize cytotoxic T-lymphocyte-associated protein 4 and programmed death-ligand 1 receptors, respectively, resulting in upregulation of the host immune response to cancer cells. There is increasing recognition of immune-mediated adverse events associated with immune therapies in patients with cancer. We present a case report of a patient who developed Miller Fisher syndrome associated with these therapies for metastatic melanoma along with a discussion of its management. |
doi_str_mv | 10.1177/1941874418778957 |
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source | PMC (PubMed Central); Sage Journals Online |
subjects | Case Reports |
title | Miller Fisher Syndrome Associated With Immunotherapy for Metastatic Melanoma |
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