Walking in orthostatic tremor modulates tremor features and is characterized by impaired gait stability

Primary orthostatic tremor (OT) is characterized by high-frequency lower-limb muscle contractions and a disabling sense of unsteadiness while standing. Patients consistently report a relief of symptoms when starting to ambulate. Here, we systematically examined and linked tremor and gait characteris...

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Bibliographic Details
Published in:Scientific reports 2018-09, Vol.8 (1), p.14152-7, Article 14152
Main Authors: Wuehr, M., Schlick, C., Möhwald, K., Schniepp, R.
Format: Article
Language:English
Subjects:
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Aged
Cerebellum
Dizziness - physiopathology
Electromyography
Female
Frequency analysis
Frequency dependence
Gait
Gait - physiology
Humanities and Social Sciences
Humans
Male
Middle Aged
multidisciplinary
Muscle, Skeletal - physiopathology
Muscles
Posture - physiology
Science
Science (multidisciplinary)
Tremor
Tremor (Muscular contraction)
Tremor - physiopathology
Walking
Walking - physiology
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Summary:Primary orthostatic tremor (OT) is characterized by high-frequency lower-limb muscle contractions and a disabling sense of unsteadiness while standing. Patients consistently report a relief of symptoms when starting to ambulate. Here, we systematically examined and linked tremor and gait characteristics in patients with OT. Tremor and gait features were examined in nine OT patients and controls on a pressure-sensitive treadmill for one minute of walking framed by two one-minute periods of standing. Tremor characteristics were assessed by time-frequency analysis of surface EMG-recordings from four leg muscles. High-frequency tremor during standing (15.29 ± 0.17 Hz) persisted while walking but was consistently reset to higher frequencies (16.34 ± 0.25 Hz; p 
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-018-32526-8