Effectiveness of monovalent rotavirus vaccine in the Philippines

Rotavirus (RV) is an important cause of diarrheal disease particularly in children aged under 5 years. Monovalent RV vaccine (RVV) was selectively introduced in 2012 in the Philippines and in July 2014 was introduced in the public health program of a province. Two RVV doses are recommended at 6 and...

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Bibliographic Details
Published in:Scientific reports 2018-09, Vol.8 (1), p.14291-8, Article 14291
Main Authors: Lopez, Anna Lena, Daag, Jedas Veronica, Esparagoza, Joel, Bonifacio, Joseph, Fox, Kimberley, Nyambat, Batmunkh, Parashar, Umesh D., Ducusin, Maria Joyce, Tate, Jacqueline E.
Format: Article
Language:English
Subjects:
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Age
Age Distribution
Child, Preschool
Children
Diarrhea
Dose-Response Relationship, Immunologic
Humanities and Social Sciences
Humans
Immunization
Infant
multidisciplinary
Philippines
Public health
Rotavirus
Rotavirus - immunology
Rotavirus Vaccines - immunology
Science
Science (multidisciplinary)
Treatment Outcome
Vaccination
Vaccine efficacy
Vaccines
Viruses
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Summary:Rotavirus (RV) is an important cause of diarrheal disease particularly in children aged under 5 years. Monovalent RV vaccine (RVV) was selectively introduced in 2012 in the Philippines and in July 2014 was introduced in the public health program of a province. Two RVV doses are recommended at 6 and 10 weeks of age. We conducted a test negative case-control evaluation to assess the effectiveness of RVV when given in a routine public health program in the Philippines. From September 2014 to August 2017, 967 children aged
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-018-32595-9