Prodromal angina and risk of 2-year cardiac mortality in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous intervention

We sought to investigate the prognostic significance of prodromal angina (PA) in unselected patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PPCI) and its additive predictive value to the GRACE score.We prospectively enrolled 301...

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Bibliographic Details
Published in:Medicine (Baltimore) 2018-09, Vol.97 (37), p.e12332-e12332
Main Authors: Ghetti, Gabriele, Bacchi Reggiani, Maria Letizia, Rosetti, Claudia, Battistini, Paola, Lanati, Gianluca, Di Dio, Maria Teresa, Corsini, Anna, Bruno, Matteo, Della Riva, Diego, Bruno, Antonio Giulio, Compagnone, Miriam, Narducci, Riccardo, Saia, Francesco, Rapezzi, Claudio, Taglieri, Nevio
Format: Article
Language:English
Subjects:
Aged
Angina Pectoris - etiology
Angina Pectoris - mortality
Female
Humans
Kaplan-Meier Estimate
Male
Middle Aged
Multivariate Analysis
Observational Study
Percutaneous Coronary Intervention - mortality
Predictive Value of Tests
Prodromal Symptoms
Proportional Hazards Models
Prospective Studies
Regression Analysis
Risk Assessment - methods
Risk Factors
Severity of Illness Index
ST Elevation Myocardial Infarction - complications
ST Elevation Myocardial Infarction - mortality
ST Elevation Myocardial Infarction - therapy
Time Factors
Treatment Outcome
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Summary:We sought to investigate the prognostic significance of prodromal angina (PA) in unselected patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PPCI) and its additive predictive value to the GRACE score.We prospectively enrolled 3015 consecutive STEMI patients undergoing PPCI. Patients were divided in 2 groups according to the presence or absence of PA. Multivariable Cox regression was used to establish the relation to 2-year cardiac mortality of PA.The mean age of the study population was 68 (±14) years; 2178 patients (72%) were male. During follow-up, 395 (13%) patients died with 278 of these (9.2%) suffering from cardiac mortality. Kaplan-Meier estimates showed a survival rate of 95% and 87% for patients with PA and no PA, respectively (log rank test 
ISSN:0025-7974
1536-5964
DOI:10.1097/MD.0000000000012332