Hormonal Correlates and Predictors of Nutritional Recovery in Malnourished African Children

ABSTRACT Background Malnourished children show variable growth responses to nutritional rehabilitation. We aimed to investigate whether these differences could be explained by variations in growth and energy-regulating hormones. Methods Quasi-experimental study: Children aged 6–24 months in rural Ga...

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Bibliographic Details
Published in:Journal of tropical pediatrics (1980) 2018-10, Vol.64 (5), p.364-372
Main Authors: Nabwera, Helen M, Bernstein, Robin M, Agbla, Schadrac C, Moore, Sophie E, Darboe, Momodou K, Colley, Mariama, Jallow, Amadou T, Bradbury, Richard, Karafin, Jennifer, Fulford, Anthony J, Prentice, Andrew M
Format: Article
Language:English
Subjects:
Anthropometry
Arm - anatomy & histology
Biomarkers - blood
C-Reactive Protein - metabolism
Case-Control Studies
Child Nutrition Disorders
Child, Preschool
Enzyme-Linked Immunosorbent Assay
Female
Gambia - epidemiology
Hormones - blood
Humans
Infant
Male
Malnutrition - blood
Malnutrition - diet therapy
Malnutrition - epidemiology
Nutrition Therapy - methods
Original Papers
Protein-Energy Malnutrition - blood
Protein-Energy Malnutrition - diet therapy
Rural Population
Saliva - metabolism
Treatment Outcome
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Summary:ABSTRACT Background Malnourished children show variable growth responses to nutritional rehabilitation. We aimed to investigate whether these differences could be explained by variations in growth and energy-regulating hormones. Methods Quasi-experimental study: Children aged 6–24 months in rural Gambia were recruited to controls if weight-for-height z-score (WHZ) > −2 (n = 22), moderate acute malnutrition if WHZ  −3 (n = 18) or severe acute malnutrition if WHZ 
ISSN:0142-6338
1465-3664
DOI:10.1093/tropej/fmx075