In Vivo Efficacy Study Showing Comparative Advantage of Bacterial Infection Prevention with Zip-type Skin Closure Device vs. Subcuticular Sutures

There remains a lack of understanding of how wound closure methods perform comparatively when exposed to patient-induced movement during healing and how they may contribute to bacterial infiltration in the wound site. The present study attempts to objectively quantify this gap. The study evaluates b...

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Bibliographic Details
Published in:Curēus (Palo Alto, CA) CA), 2018-08, Vol.10 (8), p.e3102-e3102
Main Authors: Safa, Bauback, Belson, Amir, Meschter, Carol, Kelley, Michelle, Stewart, Daren, Ichiryu, Kei, Biroc, Sandra, Storne, Eric
Format: Article
Language:English
Subjects:
Adhesives
Bacteria
Bacterial infections
Cardiac/Thoracic/Vascular Surgery
Emergency Medicine
Inflammation
Joint surgery
Orthopedics
Skin
Staphylococcus infections
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Summary:There remains a lack of understanding of how wound closure methods perform comparatively when exposed to patient-induced movement during healing and how they may contribute to bacterial infiltration in the wound site. The present study attempts to objectively quantify this gap. The study evaluates bacterial penetration and subsequent symptoms of infection of traditional sutures and an emerging tape-based, zip-type wound closure technology under physiologically relevant loading. In an in vivo model to simulate real-world conditions, the latter demonstrates better performance compared to commonly used sutures, holding the wound intact and minimizing bacterial penetration when subjected to simulated patient movement-induced stress.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.3102