BONE QUALITY MEASURED BY HR-PQCT IS NOT COMPROMISED IN TYPE 2 DIABETES—THE MAASTRICHT STUDY

Patients with type 2 diabetes mellitus (T2DM) are thought to have an increased fracture risk. Decreased bone quality could contribute to this increased risk. In this cross-sectional study of 306 participants from The Maastricht Study, we compared volumetric bone mineral density (vBMD), microarchitec...

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Bibliographic Details
Published in:Innovation in aging 2017-07, Vol.1 (suppl_1), p.1383-1383
Main Authors: deWaard, E.A., de Jong, J.J., Savelberg, H.H., van Geel, T.A., Geusens, P.P., Koster, A., van den Bergh, J.P.
Format: Article
Language:English
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Summary:Patients with type 2 diabetes mellitus (T2DM) are thought to have an increased fracture risk. Decreased bone quality could contribute to this increased risk. In this cross-sectional study of 306 participants from The Maastricht Study, we compared volumetric bone mineral density (vBMD), microarchitecture and strength at the distal radius in participants with T2DM (N=60, median HbA1c 6.9%, median diabetes duration 8.8 years) and with normal glucose metabolism (NGM, N=246) using high-resolution peripheral quantitative computed tomography. Unadjusted analyses showed increased cortical porosity (p0.05). Concluding, in this group of relatively well-treated T2DM participants bone quality may not be compromised.
ISSN:2399-5300
2399-5300
DOI:10.1093/geroni/igx004.5089